Evaluation of quantitative PCR and branched-chain DNA assay for detection of hepatitis B virus DNA in sera from hepatocellular carcinoma and liver transplant patients
Evaluation of quantitative PCR and branched-chain DNA assay for detection of hepatitis B virus DNA in sera from hepatocellular carcinoma and liver transplant patients
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DOI：
10.1128/jcm.38.5.1977-1980.2000
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发表时间：
2000-05-01
影响因子：
9.4
通讯作者：
Fan, ST
中科院分区：
文献类型：
--
作者：
Chen, T;Luk, JM;Fan, ST
本研究评估了定量PCR （Q-PCR）和支链DNA检测在血清中乙型肝炎病毒（HBV） DNA检测中的适用性。42份样品的检出率分别为81%和41%，相关系数为0.633。Q-PCR可用于高危患者HBV载量的早期监测。
This study evaluated the applicability of quantitative PCR (Q-PCR) and branched-chain DNA assays for detection of hepatitis B virus (HBV) DNA in sera. For 42 samples, the detection rates were 81 and 41%, respectively, with a correlation coefficient of 0.633. The Q-PCR is useful for early monitoring of HBV load in high-risk patients.