Effect of prostaglandin on the secretion of human growth hormone.

Effect of prostaglandin on the secretion of human growth hormone.
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前列腺素对人生长激素分泌的影响。

DOI:
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发表时间:
1971
影响因子:
5.8
通讯作者:
Yoshisato Takei
Yoshisato Takei
中科院分区:
医学2区
文献类型:
--
作者:
Haruo Ito;Goichi Momose;Takashi Katayama;Hidetoshi Takagishi;Lumi Ito;Hironori Nakajima;Yoshisato Takei

文献摘要

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静脉滴注前列腺素E_1(PGE_1)可使人生长激素(GH)分泌明显增加。刺激生长激素分泌的PGE 1管理可能是解释了一个直接或间接的作用PGE 1对垂体前叶增加环AMP,从而释放生长激素的假设。静脉输注前列腺素E_1似乎是有用的测试GH的分泌活性的方法。
ABSTRACT Intravenous drip infusion of PGE1 in man induced a marked increase of GH secretion. Stimulation of HGH secretion by PGE1 administration is possibly explained by the assumption of a direct or indirect action of PGE1 on the anterior pituitary increasing cyclic AMP, consequently releasing HGH. Intravenous infusion of PGE1 appears to be useful as a method of testing the secretory activity of GH.