Does Maternal Role Functioning Improve with Antidepressant Treatment in Women with Postpartum Depression?
Does Maternal Role Functioning Improve with Antidepressant Treatment in Women with Postpartum Depression?
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DOI：
10.1089/jwh.2007.0635
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发表时间：
2009-01-01
影响因子：
3.5
通讯作者：
Hanusa, Barbara H.
中科院分区：
文献类型：
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作者：
Logsdon, M. Cynthia;Wisner, Katherine;Hanusa, Barbara H.
目的：产后抑郁症（PPD）妇女的母亲婴儿能力降低。虽然抗抑郁治疗有效地改善了抑郁症状，但各种功能领域，例如工作和关系，并没有普遍改善治疗。在这项试点研究中，我们调查是否母亲的角色功能改善与抗抑郁治疗的妇女PPD.Methods：试点研究是一个探索性的分析，一个更大的研究。来自随机临床试验（去甲替林与舍曲林的双盲、8周试验）的一组妇女（n = 27）完成了三项母亲角色功能的结果测量：母亲角色满意度、婴儿护理调查（ICS）和母婴互动录像带。磁带进行了分析，使用儿童和照顾者相互调节编码量表和诺达斯行为codingsoftware.Results：这两种抗抑郁药同样有效地减少抑郁症状，提高整体功能和满足的母亲的角色。时间1和2之间的差异，在母婴之间的相互作用与时间（婴儿年龄的增加），而不是分配的抗抑郁药或缓解depresson.Conclusions：有效的治疗与两种抗抑郁药提高了母亲的角色，但不自我效能或母亲与婴儿的互动与PPD的妇女满意。这项研究的结果可以帮助妇女及其医疗保健提供者权衡产后短期抗抑郁治疗的益处。未来的研究应考虑与更长治疗持续时间相关的结局。
Aims: The ability to mother her infant is reduced in a woman with postpartum depression (PPD). Although antidepressant treatment effectively improves depressive symptoms, various domains of functioning, for example, work and relationships, do not universally improve with treatment. In this pilot study, we investigated whether maternal role functioning improved with antidepressant treatment in women with PPD.Methods: The pilot study was an exploratory analysis of a larger study. A subset of women (n = 27) from a randomized clinical trial (double-blind, 8-week trial of nortriptyline compared with sertraline) completed three outcome measures of maternal role functioning: gratification in the maternal role, the Infant Care Survey (ICS), and videotapes of maternal-infant interaction. The tapes were analyzed using the Child and Caregiver Mutual Regulation Coding Scale and Noldus Behavioral Coding Software.Results: The two antidepressants were equally efficacious in decreasing depressive symptoms and improving overall functioning and gratification in the maternal role. Differences between times 1 and 2 in the mother-infant interactions were related to time (increasing age of the infant) and not assignment of antidepressant or remission of depression.Conclusions: Effective treatment with two antidepressants improves gratification in the maternal role but not self-efficacy or maternal-infant interaction in women with PPD. Results of the study can help women and their healthcare providers to weigh the benefits of short-term antidepressant treatment in the postpartum period. Future studies should consider outcomes related to a longer duration of treatment.