Postoperative outcomes of esophagectomy for cancer in elderly patients
Postoperative outcomes of esophagectomy for cancer in elderly patients
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DOI：
10.1016/j.jss.2018.03.050
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发表时间：
2018-09-01
影响因子：
2.2
通讯作者：
Patti, Marco G.
中科院分区：
文献类型：
--
作者：
Schlottmann, Francisco;Strassle, Paula D.;Patti, Marco G.
背景：老年食管癌患者的数量有望增加。我们的目的是确定食管癌老年患者食管癌切除术后的预后。材料和方法：采用2000-2014年全国住院患者样本进行回顾性、基于人群的分析。本研究纳入了在住院期间行食管癌切除术的成年患者（b> = 18岁）。患者分为70组。采用多变量线性和逻辑回归来评估年龄对术后并发症、住院死亡率和医院收费的潜在影响。结果：共纳入5243例患者，其中3699例（70.6%）70岁。在研究期间，bb0 ~ 70岁患者食管切除术的年发生率无显著变化（2000年为28.4%，2014年为26.3%,P = 0.76）。老年患者发生术后心力衰竭（优势比1.59,95%可信区间[CI] 1.21, 2.09, P = 0.0009）和住院死亡率（优势比1.84,95% CI 1.39, 2.45, P < 0.0001）的可能性显著增加。在老年患者中，住院费用平均比患者高16,320美元（95% CI为3110美元，29,530美元）
Background: The number of elderly patients with esophageal cancer is expected to increase. We aimed to determine the postoperative outcomes of esophagectomy for esophageal cancer in elderly patients.Material and methods: A retrospective, population-based analysis was performed using the National inpatient sample for the period 2000-2014. Adult patients >= 18 years old (yo) diagnosed with esophageal cancer who underwent esophagectomy during their inpatient hospitalization were included. Patients were categorized into = 70 yo. Multivariable linear and logistic regressions were used to assess the potential effect of age on postoperative complications, inpatient mortality, and hospital charges.Results: Overall, 5243 patients were included, with 3699 (70.6%) 70 yo. The yearly rate of esophagectomies among patients >70 yo did not significantly changed during the study period (28.4% in 2000 and 26.3% in 2014, P = 0.76). Elderly patients were significantly more likely to have postoperative cardiac failure (odds ratio 1.59, 95% confidence interval [CI] 1.21, 2.09, P = 0.0009) and inpatient mortality (odds ratio 1.84, 95% CI 1.39, 2.45, P < 0.0001). Among the elderly patients, hospital charges were, on average, $16,320 greater (95% CI $3110, $29,530) than patients