Evaluation of the accuracy of a non-invasive hemoglobin-monitoring device in schoolchildren
Evaluation of the accuracy of a non-invasive hemoglobin-monitoring device in schoolchildren
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学童无创血红蛋白监测装置的准确性评估
DOI：
10.1016/j.pedneo.2021.05.028
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Hataya Hiroshi
中科院分区：
文献类型：
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作者：
Okazaki Kanzo;Okazaki Kaoru;Uesugi Masayoshi;Matsusima Takahiro;Hataya Hiroshi
背景缺铁性贫血（IDA）是一种以血红蛋白（Hb）水平降低为特征的儿童和青少年公共卫生问题。无创监测设备可以连续测量Hb水平，没有疼痛或不适;然而，对儿童和青少年的准确性知之甚少。这项研究估计了在这个年龄组的非侵入性Hb监测仪的准确性。MethodsParticipants是门诊患者访问东京都立儿童医疗中心的血液检测1月至2019年3月。使用非侵入性Astrim Fit监测设备和侵入性血液采集测量Hb水平，然后进行自动分析。Bland-Altman分析评估了两个measurement.ResultsOverall之间的协议，120名学童（9-15岁，51%的女性）参加。无创测量装置记录的Hb水平为13.5 ± 1.6 g/dL（平均值±标准差[SD]），而从采集的血液中获得的平均Hb水平为13.7 ± 1.7 g/dL。因此，偏倚的平均差和精密度的SD为0.17 ± 1.95 g/dL。一致性的下限和上限分别为-3.65和3.99。不存在系统性固定偏倚或比例偏倚。59人（49%）的相对误差为± 0.10。结论Astrim Fit无创血红蛋白监测仪具有极低的偏倚（或精密度），无系统偏倚（包括固定偏倚或比例偏倚），无创监测结果与采血结果呈正相关，可用于评价学龄儿童血红蛋白水平，用于健康促进或研究目的。然而，很难使用Astrim Fit设备评估儿童和青少年的Hb水平以用于诊断目的。
BackgroundIron deficiency anemia (IDA) is a public health problem in children and adolescents that is characterized by reduced hemoglobin (Hb) levels. Non-invasive monitoring devices can measure Hb levels continuously without pain or discomfort; however, little is known about their accuracy in children and adolescents. This study estimated the accuracy of a non-invasive Hb monitor in this age group.MethodsParticipants were outpatients visiting the Tokyo Metropolitan Children's Medical Center for blood tests between January and March 2019. Hb levels were measured using both non-invasive Astrim Fit monitoring devices and invasive blood collection followed by automated analysis. Bland–Altman analysis assessed the agreement between the two measurements.ResultsOverall, 120 schoolchildren (9–15 years old, 51 % female) were enrolled. The non-invasive measuring device recorded Hb levels of 13.5 ± 1.6 g/dL (mean ± standard deviation [SD]), while the mean Hb level obtained from the collected blood was 13.7 ± 1.7 g/dL. Therefore, the mean difference of bias and SD of precision was 0.17 ± 1.95 g/dL. Values of lower and upper limits of agreement were −3.65 and 3.99, respectively. There was no systematic fixed or proportion bias. Fifty-nine participants (49 %) had a relative error of ± 0.10.ConclusionThe Astrim Fit non-invasive Hb monitor can be used to evaluate Hb levels among schoolchildren for health promotion or research purposes because of its extremely low bias (or precision), no systematic biases (including fixed or proportion biases), and positive correlation between non-invasive monitoring and blood drawing. However, it is difficult to assess Hb levels in children and adolescents using the Astrim Fit device for diagnostic purposes.