Differential Substrate Specificity of Two Inositol Transporters of Bacillus subtilis
Differential Substrate Specificity of Two Inositol Transporters of Bacillus subtilis
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DOI：
10.1271/bbb.100125
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发表时间：
2010-06-01
影响因子：
1.6
通讯作者：
Yoshida, Ken-ichi
中科院分区：
文献类型：
--
作者：
Morinaga, Tetsuro;Matsuse, Takatsugu;Yoshida, Ken-ichi
枯草芽孢杆菌IolT是用于生长的主要肌醇转运蛋白，而IolF是不能支持生长的次要转运蛋白。我们发现loIT或IolF足以用于使用D-手性肌醇的适度生长。与IolT相反，IolF比肌醇更优先转运n-手性肌醇。这些结果表明IolT和IolF在底物特异性方面不同。
Bacillus subtilis IolT is the major myo-inositol transporter for growth, while IolF is a minor one unable to support growth. We found that either loIT or IolF was sufficient for moderate growth using D-chiro-inositol. Conversely to IolT, IolF transported n-chiro-inositol more preferentially than myo-inositol. These results indicate that IolT and IolF are different in substrate specificity.