Mpox in people with advanced HIV infection: a global case series

Mpox in people with advanced HIV infection: a global case series
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DOI:
10.1016/s0140-6736(23)00273-8
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发表时间:
2023-03-16
期刊:
影响因子:
168.9
通讯作者:
Orkin, Chloe M.
Orkin, Chloe M.
中科院分区:
医学1区
文献类型:
--
作者:
Mitja, Oriol;Alemany, Andrea;Orkin, Chloe M.

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在2022年多国爆发的天花疫情中,艾滋病毒感染者占受影响人数的38-50%。大多数报告的病例发生在CD 4细胞计数高的人群中,其结果与未感染艾滋病毒的人相似。新出现的数据表明,更晚期的艾滋病毒感染者的临床结局更差,死亡率更高。我们描述了一组HIV感染者和低CD 4细胞计数(CD 4
Background People living with HIV have accounted for 38-50% of those affected in the 2022 multicountry mpox outbreak. Most reported cases were in people who had high CD4 cell counts and similar outcomes to those without HIV. Emerging data suggest worse clinical outcomes and higher mortality in people with more advanced HIV. We describe the clinical characteristics and outcomes of mpox in a cohort of people with HIV and low CD4 cell counts (CD4