Resection rate curves by location along the small intestine provide perspectives on characteristics of Crohn’s disease
Resection rate curves by location along the small intestine provide perspectives on characteristics of Crohn’s disease
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按小肠位置划分的切除率曲线提供了有关克罗恩病特征的观点
DOI：
10.1111/codi.15487
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发表时间：
2020
影响因子：
3.4
通讯作者：
Unno Michiaki
中科院分区：
文献类型：
--
作者：
Suzuki Hideyuki;Watanabe Kazuhiro;Kohyama Atsushi;Ohnuma Shinobu;Karasawa Hideaki;Kajiwara Taiki;Kobayashi Minoru;Hatsuzawa Yuuri;Kamei Takashi;Unno Michiaki
克罗恩病（CD）可以影响胃肠道的任何部分;然而，CD病变的频率因部位而异。这项工作的目的是检查切除率的位置，以澄清位置的特点，小肠在外科CD cases.MethodThis是一个单中心的回顾性病例说明审查谁经历了切除CD影响小肠2014年1月至2020年2月之间。手术细节，包括小肠的长度，切除的位置和范围，确定了疾病的模式。通过规范化这些数据的切除率沿着肠的长度计算，以创建切除率curves.Results126例手术确定。切除率曲线可分为指数型和双峰型。对于初次手术，这取决于手术是否仅限于回结肠切除术。在随后的手术中，先前的回盲部切除术影响了疾病的模式。结论CD患者需行小肠切除术可分为回肠末端型（指数型）和回肠近端型（双峰型）。在未来，这种分析方法可能有助于预测任何复发性疾病的部位，但也提供了一个新的视角。
AimCrohn's disease (CD) can affect any part of the gastrointestinal tract; however, the frequency of CD lesions differs by location. This work aimed to examine resection rates by location to clarify locational characteristics of the small intestine in surgical CD cases.MethodThis was a single‐centre retrospective case note review of patients who had undergone resection for CD affecting the small intestine between January 2014 and February 2020. Operative details, including length of the small intestine, location and extent of the resection, identified the pattern of disease. By normalizing these data the resection rate along the length of the intestine was calculated to create resection rate curves.ResultsOne hundred and twenty six surgical cases were identified. The resection rate curves could be divided into two types: exponential and bimodal. For primary surgery, this depended on whether or not surgery was limited to an ileocolic resection. At subsequent surgery, a previous ileocaecal resection influenced the pattern of disease. The peaks of the bimodal curve were located at the proximal and distal ileum.ConclusionCD patients requiring resection of the small intestine can be divided into terminal ileum type (exponential type) and proximal ileum type (bimodal type). In the future this analytical method may help predict the site of any recurrent disease but also provides a new perspective on the disease.
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对健康个体进行重复拉伸或非拉伸小肠长度测量。
影响因子：
0.6
作者：
Servet Karagül;C. Kayaalp
通讯作者：
C. Kayaalp
影响因子：
3.8
作者：
Fichera, Alessandro;Lovadina, Stefano;Michelassi, Fabrizio
通讯作者：
Michelassi, Fabrizio
影响因子：
2.8
作者：
Aaltonen, Gisele;Carpelan-Holmstrom, Monika;Lepisto, Anna
通讯作者：
Lepisto, Anna
影响因子：
4.3
作者：
Yamamoto, Takayuki;Watanabe, Toshiaki
通讯作者：
Watanabe, Toshiaki