Ultrasound cervical measurement and prediction of spontaneous preterm birth in ICSI pregnancies: a prospective controlled study
Ultrasound cervical measurement and prediction of spontaneous preterm birth in ICSI pregnancies: a prospective controlled study
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DOI：
10.1016/s1472-6483(10)60269-6
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发表时间：
2009-02-01
影响因子：
4
通讯作者：
Mansour, Ragaa T.
中科院分区：
文献类型：
--
作者：
Aboulghar, Mona M.;Aboulghar, Mohamed A.;Mansour, Ragaa T.
对222例双胎妊娠、122例单胎妊娠和51例自然单胎妊娠进行了经阴道超声测量宫颈长度的前瞻性对照研究。早产定义为：534周。获得了193例双胎妊娠(A组)、102例单胎妊娠(B组)和51例自然单胎妊娠(Q组)的完整资料。三组中期宫颈长度差异无统计学意义：A组37.6±7.1 mm，B组37.2±-7.2 mm，C组39.2±-5.4 mm。A组早产发生率为30.5%，B组为17.6%，C组为3.9%，差异有统计学意义(P=0.011)。A组预测早产最佳宫颈长度截断点的ROC曲线为38.05 mm。敏感度67%，特异度50%。阳性预测值(PPV)为37.7，阴性预测值(NPV)为78.1。B组为33.05 NIM，敏感性50%，特异性70%，PPV 34.6，NPV 88。L与自然妊娠的情况相反，ICSI单胎和双胎妊娠的中期宫颈长度测量不是早产的预测因素。
A prospective controlled study was performed in which transvaginal ultrasound measurement of cervical length was compared in 222 twin ICSI pregnancies, 122 singleton ICSI pregnancies and 51 spontaneous singleton pregnancies. Preterm birth was defined as :534 weeks. Full data were obtained for 193 twin pregnancies (group A), 102 singleton pregnancies (group B) and 51 spontaneous singleton pregnancies (group Q. Cervical length at midterm was not statistically different between the three groups: group A, 37.6 +/- 7.1 mm; group B, 37.2 +/- 7.2 mm; and group C, 39.2 +/- 5.4 mm. The incidence of preterm birth was statistically different between groups: 30.5% in group A; 17.6% in group B; and 3.9% in group C (P = 0.011). The ROC curve for optimum cut-off of cervical length in prediction of preterm birth for group A was 38.05 mm. sensitivity 67%, specificity 50%. positive predictive value (PPV) 37.7, and negative predictive value (NPV) 78.1. For group B the data were 33.05 nim, sensitivity 50%, specificity 70%, PPV 34.6, and NPV 88. L Contrary to the situation for spontaneous pregnancies, midtrimester cervical length measurement in ICSI singleton and twin pregnancies is not a predictor for preterm birth.