ENHANCEMENT OF ANTITUMOR EFFECT OF CYTO-TOXIC AGENTS BY BESTATIN
ENHANCEMENT OF ANTITUMOR EFFECT OF CYTO-TOXIC AGENTS BY BESTATIN
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DOI：
10.7164/antibiotics.38.411
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发表时间：
1985-01-01
影响因子：
3.3
通讯作者：
UMEZAWA, H
中科院分区：
文献类型：
--
作者：
ABE, F;SHIBUYA, K;UMEZAWA, H
Bestatin增强丝裂霉素C、5-氟尿嘧啶和顺式二氯二氨铂对BALB/c小鼠结肠腺癌26的抗肿瘤作用。增强作用依赖于给药时间表。用细胞毒性药物治疗后给予Bestatin比治疗前更有效。
Bestatin enhanced the antitumor effects of mitomycin C, 5-fluorouracil and cis-dichlorodiammineplatinum against a syngeneic solid tumor of colon adenocarcinoma 26 in BALB/c mice. The enhancement was dependent on administration schedule. Bestatin administration after treatment with the cytotoxic agents was more effective than that made before the treatment.