South Korea's COVID-19 Infection Status: From the Perspective of Re-positive Test Results After Viral Clearance Evidenced by Negative Test Results
South Korea's COVID-19 Infection Status: From the Perspective of Re-positive Test Results After Viral Clearance Evidenced by Negative Test Results
复制标题
DOI：
10.1017/dmp.2020.168
复制
发表时间：
2020-12-01
影响因子：
2.7
通讯作者：
Kang, Yun-Jung
中科院分区：
文献类型：
--
作者：
Kang, Yun-Jung
2020年1月19日，中国武汉首次确诊一例冠状病毒病（COVID-19），该病毒从国外流入韩国，开始在韩国发生。尽管韩国已经大幅减少了新确诊病例的数量，并正在以其模范的疾病预防政策稳定局势，但仍然存在问题。这些病例在聚合酶链反应（PCR）（基因扩增）测试中显示阴性结果，因为COVID-19病毒已无法检测到，但在短时间后重新呈阳性。中央临床委员会认定，这些COVID-19病毒清除后的再阳性病例是由于检测方法的局限性;认为在检测过程中，残留在康复患者体内的“死病毒”的遗传物质被放大。理解上述证据，COVID-19的再阳性病例没有传染性;病毒甚至没有重新激活。然而，由于缺乏这方面的研究成果，还需要进一步的研究。在我们能够确定之前，应该保持社交距离和其他此类政策。
Coronavirus disease (COVID-19) started to occur in South Korea by means of inflow of the virus from abroad, when a case from Wuhan, China, was first confirmed on January 19, 2020. Although South Korea has drastically reduced the number of new confirmed cases and is stabilizing the situation with its exemplary disease prevention policies, there remains a problem. These are cases that had shown negative results to polymerase chain reaction (PCR) (gene amplification) tests as the COVID-19 virus had become undetectable but turned re-positive after a short period. The Central Clinical Committee determined that these re-positive cases after COVID-19 viral clearance are due to the limits of the test method; it is considered that the genetic material of the "dead virus" remaining in a recovered patient's body is amplified during the test process. Comprehending the above evidence, re-positive cases of COVID-19 are not infectious; the virus is not even reactivated. However, further research is required as we lack research results on this subject. Until we can be sure, social distancing and other such policies should be maintained.