Diagnostic criteria for diabetes mellitus and other categories of glucose intolerance: 1997 criteria by the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus (ADA), 1998 WHO Consultation criteria, and 1985 WHO criteria
Diagnostic criteria for diabetes mellitus and other categories of glucose intolerance: 1997 criteria by the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus (ADA), 1998 WHO Consultation criteria, and 1985 WHO criteria
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DOI：
10.1016/s0168-8227(99)00008-x
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发表时间：
1999-04-01
影响因子：
5.1
通讯作者：
Sriphrapradaeng, A
中科院分区：
文献类型：
--
作者：
Puavilai, G;Chanprasertyotin, S;Sriphrapradaeng, A
为了比较1997年ADA对糖尿病和其他类型葡萄糖耐受不良的诊断标准/1998年WHO咨询标准与1985年WHO标准，我们分析了在泰国Ramathibodi医院糖尿病筛查诊所对1051名无糖尿病病史的高风险受试者进行的75克口服葡萄糖耐量试验（OGTT）的数据。男性372例，女性679例，年龄（平均±sd）。= 50.3 + / - 12.55岁,体重指数= 25.62 + / - 4.39公斤/米(2)。如果空腹血糖（FPG）按照最近的建议使用，那么分别有54.1%、20.3%和25.5%的病例被归类为正常、空腹血糖受损和糖尿病。以1985年WHO标准为参考的全OGTT诊断糖尿病时，IFG患者2小时血糖≥11.1 mmol/l时，FPG≥7 mmol/l的敏感性为57.7%，特异性为97.4%，阳性预测值为94.0%，阴性预测值为76.4%,53.7%。1997年ADAI/1998年世卫组织咨询标准和1985年世卫组织关于全面OGTT的标准产生了类似的总体结果。FPG（大于等于7 mmol/l）对糖尿病的诊断不敏感。此外，大约一半的IFG患者实际上是糖尿病患者。因此，OGTT仍然是诊断糖尿病和分类各种类型葡萄糖耐受不良的有价值的测试。1999爱思唯尔科学爱尔兰有限公司版权所有。
To compare 1997 ADA diagnostic criteria for diabetes mellitus and other categories of glucose intolerance/1998 WHO Consultation criteria versus 1985 WHO criteria, we analyzed data from a 75-g oral glucose tolerance test (OGTT) performed on 1051 high-risk subjects without medical history of diabetes at Diabetes Screening Clinic, Ramathibodi Hospital, Thailand. There were 372 males and 679 females, aged (mean +/- S.D.) = 50.3 +/- 12.55 years, BMI = 25.62 +/- 4.39 kg/m(2). If fasting plasma glucose (FPG) was used as recently recommended then 54.1, 20.3, and 25.5% of cases were classified as normal, impaired fasting glucose (IFG), and diabetic, respectively. In diagnosing diabetes using a full OGTT based on the 1985 WHO criteria as the reference test, FPG greater than or equal to 7 mmol/l had a sensitivity of 57.7%, specificity of 97.4%, positive predictive value of 94.0%, and negative predictive value of 76.4% 53.7%, of subjects with IFG had 2-h plasma glucose greater than or equal to 11.1 mmol/l. The 1997 ADAI/1998 WHO Consultation criteria and 1985 WHO criteria for a full OGTT yield similar overall results. FPG (greater than or equal to 7 mmol/l) was not sensitive for diagnosing diabetes. Moreover, about half of the subjects with IFG were actually diabetic. Therefore, OGTT remains a valuable test in diagnosing diabetes and classifying various categories of glucose intolerance. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.