Reversible Ag+-crosslinked DNA hydrogels
Reversible Ag+-crosslinked DNA hydrogels
复制标题
DOI：
10.1039/c3cc49140d
复制
发表时间：
2014-01-01
影响因子：
4.9
通讯作者：
Willner, Itamar
中科院分区：
文献类型：
--
作者：
Guo, Weiwei;Qi, Xiu-Juan;Willner, Itamar
DNA水凝胶由Y形核酸亚基或核酸官能化的丙烯酰胺链组成，经历可切换的凝胶到溶液的转变。胞嘧啶Ag+-胞嘧啶复合物的Ag+刺激形成导致单元交联以产生水凝胶，而半胱胺诱导的Ag+离子消除将水凝胶解离成溶液相。
DNA hydrogels, consisting of Y-shaped nucleic acid subunits or of nucleic acid-functionalized acrylamide chains, undergo switchable gel-to-solution transitions. The Ag+-stimulated formation of cytosine Ag+-cytosine complexes results in the crosslinking of the units to yield the hydrogels, while the cysteamine-induced elimination of the Ag+ ions dissociates the hydrogels into a solution phase.