Plasmid DNA in Treponema pallidum (Nichols): potential for antibiotic resistance by syphilis bacteria.
Plasmid DNA in Treponema pallidum (Nichols): potential for antibiotic resistance by syphilis bacteria.
复制标题
梅毒螺旋体（尼科尔斯）中的质粒 DNA：梅毒细菌对抗生素产生耐药性的潜力。
DOI：
10.1126/science.6264606
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
Miller,JN
中科院分区：
文献类型：
--
作者：
Norgard,MV;Miller,JN
在人类病原体梅毒螺旋体（Treponema pallidum，Nichols）中发现一种质粒DNA结构（分子量约为7.5 × 106）。不能从兔宿主组织中分离该质粒，并且该质粒与兔DNA完全缺乏DNA同源性，证实了其梅毒螺旋体起源。观察文件一个新的认识和潜在的重大遗传能力梅毒螺旋体。
A plasmid DNA structure (approximate molecular weight = 7.5 × 106) was identified in the human pathogenTreponema pallidum(Nichols). The inability to isolate this plasmid from rabbit host tissue and the total lack of DNA homology of the plasmid with rabbit DNA has confirmed itsTreponema pallidumorigin. The observation documents a newly recognized and potentially significant genetic capability forTreponema pallidum.