Time course of 8‐methoxypsoralen concentrations in skin and plasma after topical (bath and cream) and oral administration of 8‐methoxypsoralen
Time course of 8‐methoxypsoralen concentrations in skin and plasma after topical (bath and cream) and oral administration of 8‐methoxypsoralen
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DOI：
10.1067/mcp.2002.121908
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发表时间：
2002-03
影响因子：
6.7
通讯作者：
I. Tegeder;L. Bräutigam;M. Podda;Silke Meier;R. Kaufmann;G. Geisslinger;M. Grundmann‐Kollmann
中科院分区：
文献类型：
--
作者：
I. Tegeder;L. Bräutigam;M. Podda;Silke Meier;R. Kaufmann;G. Geisslinger;M. Grundmann‐Kollmann
8-甲氧基补骨脂素联合紫外线 A 照射（PUVA 疗法）是多种皮肤病的标准治疗方法。描述了以下三种变体：口服、沐浴或霜剂 PUVA。为了达到最佳治疗效果，紫外线A照射应在光敏性最大时进行，即8-甲氧基补骨脂素组织浓度最大时进行。
The combination of 8‐methoxypsoralen with ultraviolet A exposure (PUVA therapy) is a standard treatment for a variety of dermatoses. The following three variants have been described: oral, bath, or cream PUVA. To achieve optimal therapeutic effects, ultraviolet A irradiation should be performed at the time of maximum photosensitivity, that is, at the time of maximum 8‐methoxypsoralen tissue concentrations.