Circulating glucose and insulin in surgery for insulomas.
Circulating glucose and insulin in surgery for insulomas.
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脑岛瘤手术中的循环葡萄糖和胰岛素。
DOI：
10.1001/jama.1971.03190080034007
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发表时间：
1971
期刊：
影响因子：
--
通讯作者：
E. Moffitt
中科院分区：
文献类型：
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作者：
N. Schnelle;G. Molnar;D. O. Ferris;J. Rosevear;E. Moffitt
胰岛素瘤手术期间连续血糖和血浆免疫反应性胰岛素测量在6例患者中具有临床意义。在肿瘤切除后的最初30分钟内，平均血糖浓度上升了40 mg/100 ml/hr，此时原位没有进一步的功能性胰岛细胞瘤。该信息在15分钟延迟后提供给外科医生。随后确定的胰岛素水平证实了基于葡萄糖测量的假设。除了帮助外科医生切除必要的最少量胰腺外，这些测量还提高了患者在麻醉期间潜在危险的低血糖的安全性。5例患者术前行腹腔动脉造影。它们有助于两名患者的肿瘤定位，并在第三名患者中被回顾性地识别出正确的肿瘤位置。
Serial blood glucose and plasma immunoreactive insulin measurements during operations for insulomas were clinically useful in six patients. Mean blood glucose concentration rose by 40 mg/100 ml/hr during the initial 30 minutes after tumor removal, when no further functioning insuloma remained in situ. This information was available to the surgeon with a 15-minute delay. Insulin levels determined subsequently confirmed the assumptions based on glucose measurements. In addition to helping the surgeon to resect the least amount of pancreas necessary, these measurements enhanced the patient's safety from potentially dangerous hypoglycemia during anesthesia. Preoperative celiac arteriograms were done in five patients. They were helpful in localizing tumors in two patients and were retrospectively recognized to have correctly indicated the location of the tumor in a third patient.