Sucupira as a Potential Plant for Arthritis Treatment and Other Diseases.
Sucupira as a Potential Plant for Arthritis Treatment and Other Diseases.
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DOI：
10.1155/2015/379459
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Cardoso ML
中科院分区：
文献类型：
--
作者：
Hoscheid J;Cardoso ML
翼龙属的树木，通常被称为“sucupira-branca”或“faveira”，原产于巴西中部。Pterodon果实传统上用于民族医学作为输液，小剂量，并定期作为抗风湿，抗炎，滋补和净化剂。存在于Pterodon类中的各种化合物通常是水不溶性的，并且衍生自高分子量五肽单元的融合。科学研究表明，从Pterodon物种中分离出的主要化合物是具有vouacapane骨架的线性和/或四环二萜，这部分地构成了水果衍生油的药理活性。来自翼龙属物种的材料具有几种生物学特性，例如镇痛、抗炎和抗癌作用。因此，最近的研究试图将这些提取物微胶囊化，以保护它们免受潜在的化学降解，并提高它们的水溶性，确保最终产品的更高稳定性和质量。这篇综述简要概述了现有的科学证据的生物活性和毒性的翼龙物种除了其他重要方面，包括植物化学和技术特征。
Trees of the genus Pterodon, commonly known as “sucupira-branca” or “faveira,” are native to central Brazil. The Pterodon fruits are traditionally used in ethnomedicine as an infusion, in small doses, and at regular time intervals as an antirheumatic, anti-inflammatory, tonic, and depurative agent. The various compounds present in the Pterodon class are, generally, water-insoluble and derived from the fusion of high-molecular weight pentacarbonate units. Scientific research has shown that the major compounds isolated from Pterodon species are linear and/or tetracyclic diterpenes with vouacapane skeletons that partly underlie the pharmacological activities of the fruit-derived oil. Material from Pterodon species has several biological properties, such as analgesic, anti-inflammatory, and anticancer effects. Therefore, recent studies have sought to microencapsulate these extracts to protect them from potential chemical degradation and improve their water solubility, ensuring greater stability and quality of the end products. This review presents a succinct overview of the available scientific evidence of the biological activity and toxicity of Pterodon species in addition to other important aspects, including phytochemical and technological features.