Effects of dietary D-psicose on diurnal variation in plasma glucose and insulin concentrations of rats
Effects of dietary D-psicose on diurnal variation in plasma glucose and insulin concentrations of rats
复制标题
DOI：
10.1271/bbb.60036
复制
发表时间：
2006-09-01
影响因子：
1.6
通讯作者：
Izumori, Ken
中科院分区：
文献类型：
--
作者：
Matsuo, Tatsuhiro;Izumori, Ken
在大鼠中研究了饮食中补充正阿洛酮糖对血浆葡萄糖和胰岛素浓度的昼夜变化的影响。将四十八只雄性 Wistar 大鼠分为四组。除对照组外，各组均喂食 5% D-果糖、n-阿洛酮糖或 psico-稀有糖（D-果糖和 D-阿洛酮糖 3:1 混合物），持续 8 周。与对照组和果糖组相比，阿洛酮糖和阿洛酮稀糖组的血浆葡萄糖水平在一天中的任何时间都较低，血浆胰岛素水平较高。阿洛酮糖组的体重增加明显低于对照组和果糖组。阿洛酮糖组餐前和餐后的肝糖原含量均高于对照组和果糖组。这些结果表明补充正阿洛酮糖可以降低血浆葡萄糖水平并减少体内脂肪积累。因此，正阿洛酮糖可能有助于预防糖尿病患者的餐后高血糖。
The effects of supplemental n-psicose in the diet on diurnal variation in plasma glucose and insulin concentrations were investigated in rats. Forty-eight male Wistar rats were divided into four groups. Each group except for the control group was fed a diet of 5% D-fructose, n-psicose, or psico-rare sugar (3:1 mixture of D-fructose and D-psicose) for 8 weeks. Plasma glucose levels were lower and plasma insulin levels were higher at all times of day in the psicose and psico-rare sugar groups than in the control and fructose groups. Weight gain was significantly lower in the psicose group than in the control and fructose groups. Liver glycogen content, both before and after meals was higher in the psicose group than in the control and fructose groups. These results suggest that supplemental n-psicose can lower plasma glucose levels and reduce body fat accumulation. Hence, n-psicose might be useful in preventing postprandial hyperglycemia in diabetic patients.