Laser peripheral iridotomy in eyes with narrow drainage angles: Ultrasound biomicroscopy outcomes. The Liwan eye study
Laser peripheral iridotomy in eyes with narrow drainage angles: Ultrasound biomicroscopy outcomes. The Liwan eye study
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DOI：
10.1016/j.ophtha.2006.11.032
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发表时间：
2007-08-01
期刊：
影响因子：
13.7
通讯作者：
Foster, Paul J.
中科院分区：
文献类型：
--
作者：
He, Mingguang;Friedman, David S.;Foster, Paul J.
目的：采用超声生物显微镜（UBM）评估激光周边虹膜切开术（LPI）对疑闭角型患者眼前节解剖结构的短期影响。设计：前瞻性干预研究。参与者：在中国广州进行的一项基于人群的调查中确定为年龄在50-79岁之间的房角闭合疑似患者。干预：对随机选择的1只眼睛进行激光周边虹膜切开术。干预前及干预后2周分别行超声生物显微镜检查。主要结局指标：虹膜小梁接触（ITC）的眼睛比例，以及UBM参数的变化，包括开角距离（AOD）、虹膜厚度（IT）、虹膜曲率、虹膜睫状突距离、小梁-睫状突距离（TCPD）和巩膜棘至虹膜插入距离（SS-IR）。结果101例符合条件的受试者中，共有72例参加了研究。UBM确定的ITC在>= 1象限中的比例从LPI前的95%（68/72）下降到LPI后的59%（42/72）。LPI后，250 μ m处的平均AOD从0.064 mm（标准差[SD]，0.052）增加到0.085（0.052）mm（P
Purpose: To assess the short-term effect of laser peripheral iridotomy (LPI) on anterior segment anatomy in angle-closure suspects using ultrasound biomicroscopy (UBM). Design: Prospective intervention study. Participants: Persons identified as angle-closure suspects aged 50-79 years from a population-based survey in Guangzhou, China. Intervention: Laser peripheral iridotomy was performed on 1 randomly selected eye. Ultrasound biomicroscopy examination was carried out before and 2 weeks after the intervention. Main Outcome Measures: Proportion of eyes with iridotrabecular contact (ITC), as well as changes in UBM parameters including angle opening distance (AOD), iris thickness (IT), iris curvature, iris ciliary process distance, trabecular-ciliary process distance (TCPD), and scleral spur to iris insertion distance (SS-IR). Results A total of 72 of 101 eligible subjects participated in the study. The proportion of people with UBM-identified ITC in >= 1 quadrant dropped from 95% (68/72) before to 59% (42/72) after LPI. After LPI, the mean AOD at 250 microns increased from 0.064 mm (standard deviation [SD], 0.052) to 0.085 (0.052) mm (P