Prevalence of SARS-CoV-2 specific neutralising antibodies in blood donors from the Lodi Red Zone in Lombardy, Italy, as at 06 April 2020

Prevalence of SARS-CoV-2 specific neutralising antibodies in blood donors from the Lodi Red Zone in Lombardy, Italy, as at 06 April 2020
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DOI:
10.2807/1560-7917.es.2020.25.24.2001031
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发表时间:
2020-06-18
期刊:
影响因子:
19
通讯作者:
Baldanti, Fausto
Baldanti, Fausto
中科院分区:
医学2区
文献类型:
--
作者:
Percivalle, Elena;Cambie, Giuseppe;Baldanti, Fausto

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我们评估了居住在意大利洛迪红区的献血者(BD)的SARS-CoV-2 RNA和中和抗体。在2020年2月20日之后招募的390名BD中,当伦巴第发现首例COVID-19病例时,91名(23%)年龄在19-70岁之间的人抗体呈阳性。在另外17个(4.3%)BD中检测到病毒RNA,约28%(108/390)有病毒暴露证据。早在2月12日采集的5个储存样本血清反应呈阳性。
We evaluated SARS-CoV-2 RNA and neutralising antibodies in blood donors (BD) residing in the Lodi Red Zone, Italy. Of 390 BDs recruited after 20 February 2020 - when the first COVID-19 case in Lombardy was identified, 91 (23%) aged 19-70 years were antibody positive. Viral RNA was detected in an additional 17 (4.3%) BDs, yielding ca 28% (108/390) with evidence of virus exposure. Five stored samples collected as early as 12 February were seropositive.