Choice of antihypertensive agent in isolated systolic hypertension and isolated diastolic hypertension: A secondary analysis of the ALLHAT trial.
Choice of antihypertensive agent in isolated systolic hypertension and isolated diastolic hypertension: A secondary analysis of the ALLHAT trial.
复制标题
单纯性收缩期高血压和单纯性舒张期高血压的抗高血压药物选择：ALLHAT 试验的二次分析。
DOI：
10.1016/j.ahj.2022.07.006
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发表时间：
2022
影响因子：
4.8
通讯作者：
Nanna,MichaelG
中科院分区：
文献类型：
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作者：
Wang,StephenY;Hanna,JonathanM;Gongal,Prajesh;Onuma,OyereK;Nanna,MichaelG
尽管有广泛的治疗建议，但比较不同降压药在单纯收缩期高血压或单纯舒张期高血压患者中疗效的已发表报告有限。本研究是对预防心脏病发作的降压和降脂治疗试验的二次分析。我们比较了单纯收缩期高血压或单纯舒张期高血压患者使用氯噻酮、氯噻酮或赖诺普利对合并冠心病、卒中或全因死亡率的主要转归。
Despite broad treatment recommendations, there are limited published reports comparing the efficacy of different antihypertensive agents in patients with isolated systolic hypertension or isolated diastolic hypertension. This study was a secondary analysis of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial. We compared the use of chlorthalidone, amlodipine, or lisinopril on the primary outcome of combined coronary heart disease, stroke, or all-cause mortality in patients with isolated systolic hypertension or isolated diastolic hypertension.