The guinea-pig is not a rodent
The guinea-pig is not a rodent
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DOI：
10.1038/381597a0
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发表时间：
1996-06-13
期刊：
影响因子：
64.8
通讯作者：
Arnason, U
中科院分区：
文献类型：
--
作者：
DErchia, AM;Gissi, C;Arnason, U
1991年，Graur等人提出了豚鼠（Cavia porcellus）是否是啮齿动物的问题(1)。他们认为，豚鼠和肌形啮齿类动物在肌形啮齿类动物与灵长类动物和偶蹄动物的谱系分离之前就已经分化了。一些研究结果已经被报道，支持和反对这种系统发育，从而突出了分子分析在哺乳动物系统发育中的有效性问题。在这里，我们提出了基于豚鼠线粒体全基因组序列的发现，这与啮齿动物的单系性强烈矛盾。这些结论是基于形态学遗传基因提供的累积证据和使用三种不同的分析方法，没有一种方法将豚鼠与肌型啮齿动物联系起来。除了系统发育的结论外，我们还提请注意几个因素，这些因素对基于分子数据的系统发育分析的有效性很重要。
IN 1991 Graur et al. raised the question of whether the guinea-pig, Cavia porcellus, is a rodent(1). They suggested that the guinea-pig and myomorph rodents diverged before the separation between myormorph rodents and a lineage leading to primates and artiodactyls. Several findings have since been reported, both for and against this phylogeny, thereby highlighting the issue of the validity of molecular analysis in mammalian phylogeny. Here we present findings based on the sequence of the complete mitochondrial genome of the guinea-pig, which strongly contradict rodent monophyly. The conclusions are based on the cumulative evidence provided by orthologically inherited genes and the use of three different analytic al methods, none of which joins the guinea-pig with myomorph rodents. In addition to the phylogenetic conclusions, we also draw attention to several factors that are important for the validity of phylogenetic analysis based on molecular data.