Collagenous crystalloids in pleomorphic adenoma of the parotid gland.
Collagenous crystalloids in pleomorphic adenoma of the parotid gland.
复制标题
腮腺多形性腺瘤中的胶原晶体。
DOI：
10.1002/dc.24149
复制
发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Tsuta K.
中科院分区：
文献类型：
--
作者：
Okano K;Arimoto T;Ishida M;Sandoh K;Fujisawa T;Iwai H;Tsuta K.
一名44岁的日本男性，没有明显的既往史，出现左侧腮腺肿胀。进行细针穿刺细胞学检查。常规染色的巴氏涂片显示粘液样背景中有丰富的上皮细胞簇。大多数集群是有凝聚力的，然而，在粘液样背景中观察到解离的细胞。这些上皮细胞表现出温和的，圆形至卵圆形的细胞核，无核仁。Giemsa染色显示粘液物质异染。这些细胞学特征是多形性腺瘤（PA）的典型特征。一个值得注意的发现是上皮簇内存在圆形至椭圆形结构（图1A，1B）。这些结构包括径向排列的针状晶体（图1A，1B）。切除的左侧腮腺肿瘤的组织学检查表明，肿瘤是由纤维囊，此外，上皮细胞和肿瘤性肌上皮细胞的增殖内观察到的粘液软骨材料。观察到管状形成。上皮细胞和肿瘤性肌上皮细胞均呈淡圆形至卵圆形，
A 44-year-old Japanese male without significant past history presented with swelling of the left parotid gland. Fine-needle aspiration cytological examination was performed. Conventionally-stained Papanicolaou smear revealed abundant epithelial cell clusters in a myxoid background. Most clusters were cohesive; however, dissociated cells in a myxoid background were observed. These epithelial cells exhibited bland, round-to-oval nuclei without nucleoli. Myxoid material showed metachromasia by Giemsa staining. These cytological features were typical for pleomorphic adenoma (PA). A notable finding was the presence of round-to-oval structures within the epithelial clusters (Fig. 1A, 1B). These structures comprised radially arranged needle-shaped crystalloids (Fig. 1A, 1B). Histopathological examination of the resected left parotid gland tumor demonstrated that the tumor was well-circumscribed by a fibrous capsule; furthermore, proliferation of epithelial and neoplastic myoepithelial cells was observed within a myxochondroid material. Tubular formation was observed. Both epithelial and neoplastic myoepithelial cells had bland, round-to-oval