Serial measurements increase the accuracy of laser Doppler assessment of burn wounds
Serial measurements increase the accuracy of laser Doppler assessment of burn wounds
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DOI：
10.1097/01.bcr.0000076091.79370.56
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发表时间：
2003-07-01
期刊：
影响因子：
--
通讯作者：
Hunt, JL
中科院分区：
文献类型：
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作者：
Mileski, WJ;Atiles, L;Hunt, JL
通过基于外观和感觉对伤口进行临床评估来判断烧伤深度的传统方法仍然广泛使用，但会受到检查者的个体差异的影响。除了烧伤伤口处理的临床困难之外，伤口评估的观察者依赖性也使烧伤伤口治疗的临床试验变得复杂。使用带有多通道探头的激光多普勒流量计来测量烧伤创面灌注，作为预测伤口结果的工具。使用激光多普勒血流计进行的连续测量对于识别不愈合伤口的特异性为 88%，阳性预测值为 81%。这些结果表明激光多普勒血流计是烧伤创面评估的潜在有用工具。
Traditional methods of judging burn depth by clinical evaluation of the wound based on appearance and sensation remain in wide use but are subject to individual variation by examiner. In addition to the clinical difficulties with burn wound management, observer dependency of wound assessment complicates clinical trials of burn wound therapy. A laser Doppler flowmeter with a multichannel probe was used to measure burn wound perfusion as a tool to predict wound outcome. Serial measurement with laser Doppler flowmetry had an 88% specificity and a positive predictive value of 81% for identifying nonhealing wounds. These results suggest that laser Doppler flowmetry is a potentially useful tool for burn wound assessment.