Compton imaging for medical applications
Compton imaging for medical applications
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DOI：
10.1007/s12194-022-00666-2
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发表时间：
2022-07
影响因子：
1.6
通讯作者：
H. Tashima;T. Yamaya
中科院分区：
文献类型：
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作者：
H. Tashima;T. Yamaya
康普顿成像利用称为康普顿散射的非弹性散射，使用由前层中的散射体检测器和后层中的吸收体检测器组成的康普顿相机。这种方法是为天文学开发的，近年来，环境和医学应用的研究和开发一直在积极进行。康普顿成像可以在从几百keV到几MeV的宽能量范围内辨别伽马射线。因此，它有望应用于核医学中的多核素同时成像和粒子治疗中用于距离验证的瞬发γ射线成像。另外，期望实现多伽马符合成像，其允许使用同时发射多个伽马射线的核素（诸如与正电子衰变同时发射单个伽马射线的核素）从单个符合事件确定源位置。本文介绍了康普顿成像在医学领域的实际应用，包括在体研究的各种努力，并讨论了它的前景。
Compton imaging exploits inelastic scattering, known as Compton scattering, using a Compton camera consisting of a scatterer detector in the front layer and an absorber detector in the back layer. This method was developed for astronomy, and in recent years, research and development for environmental and medical applications has been actively conducted. Compton imaging can discriminate gamma rays over a wide energy range from several hundred keV to several MeV. Therefore, it is expected to be applied to the simultaneous imaging of multiple nuclides in nuclear medicine and prompt gamma ray imaging for range verification in particle therapy. In addition, multiple gamma coincidence imaging is expected to be realized, which allows the source position to be determined from a single coincidence event using nuclides that emit multiple gamma rays simultaneously, such as nuclides that emit a single gamma ray simultaneously with positron decay. This review introduces various efforts toward the practical application of Compton imaging in the medical field, including in vivo studies, and discusses its prospects.