Assessment of a treatment guideline to improve home management of malaria in children in rural south-west Nigeria.
Assessment of a treatment guideline to improve home management of malaria in children in rural south-west Nigeria.
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DOI：
10.1186/1475-2875-7-24
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发表时间：
2008-01-29
期刊：
影响因子：
3
通讯作者：
Kale OO
中科院分区：
文献类型：
--
作者：
Ajayi IO;Falade CO;Bamgboye EA;Oduola AM;Kale OO
许多患有疟疾的尼日利亚儿童在家中接受治疗。治疗大多是不正确的，因为护理人员对适当和正确剂量的药物缺乏了解。在尼日利亚西南部的两个农村卫生区进行了一项比较研究，以确定针对护理人员的指导方针在使用氯喹治疗发热儿童中的有效性。进行了基线和干预后的知识、态度和做法住户调查。干预战略包括在选定的社区培训一批核心母亲（“母亲培训员”），使其了解疟疾的正确治疗方法，并向每个家庭分发新制定的治疗指南。“母亲培训员”向其社区传播关于疟疾和使用该准则的教育信息。经过一年的干预，人们对疟疾的病因、预防和治疗的了解有所增加。许多受访者（70.4%）表示，他们在每次治疗儿童疟疾时都使用该指南。在干预组中，在家治疗儿童的正确使用氯喹的比例从基线时的2.6%显著增加到干预后的52.3%，而对照组为4.2%至12.7%。在家中使用氯喹治疗发热儿童的患者开始治疗的时间明显早于带孩子去药店或卫生机构的患者（p < 0.005）。母亲们认为该准则明确而有用。母亲培训员也被认为是有效和可接受的。在充分培训的情况下使用该指南显著提高了在家中使用氯喹治疗疟疾的正确性。建议采用这种干预模式，以提高家庭用药的依从性。需要调查在社区一级采用青蒿素类复方疗法的可行性。
Many Nigerian children with malaria are treated at home. Treatments are mostly incorrect, due to caregivers' poor knowledge of appropriate and correct dose of drugs. A comparative study was carried out in two rural health districts in southwest Nigeria to determine the effectiveness of a guideline targeted at caregivers, in the treatment of febrile children using chloroquine. Baseline and post intervention knowledge, attitude and practice household surveys were conducted. The intervention strategy consisted of training a core group of mothers ("mother trainers") in selected communities on the correct treatment of malaria and distributing a newly developed treatment guideline to each household. "Mother trainers" disseminated the educational messages about malaria and the use of the guideline to their communities. Knowledge of cause, prevention and treatment of malaria increased with the one-year intervention. Many, (70.4%) of the respondents stated that they used the guideline each time a child was treated for malaria. There was a significant increase in the correct use of chloroquine from 2.6% at baseline to 52.3% after intervention among those who treated children at home in the intervention arm compared with 4.2% to 12.7% in the control arm. The correctness of use was significantly associated with use of the guideline. The timeliness of commencing treatment was significantly earlier in those who treated febrile children at home using chloroquine than those who took their children to the chemist or health facility (p < 0.005). Mothers considered the guideline to be explicit and useful. Mother trainers were also considered to be effective and acceptable. The use of the guideline with adequate training significantly improved correctness of malaria treatment with chloroquine at home. Adoption of this mode of intervention is recommended to improve compliance with drug use at home. The applicability for deploying artemisinin-based combination therapy at the community level needs to be investigated.
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DOI：
10.1016/s0035-9203(01)90252-4
发表时间：
2001-05-01
影响因子：
2.2
作者：
Okonkwo, PO;Akpala, CO;Nwaiwu, O
通讯作者：
Nwaiwu, O
影响因子：
2
作者：
Salako, LA;Brieger, WR;Akinlade, CO
通讯作者：
Akinlade, CO
影响因子：
3.3
作者：
Marsh, VM;Mutemi, WM;Marsh, K
通讯作者：
Marsh, K
影响因子：
3.2
作者：
Brieger, WR;Osamor, PE;Otusanya, SA
通讯作者：
Otusanya, SA
影响因子：
5.4
作者：
Baume, C;Helitzer, D;Kachur, SP
通讯作者：
Kachur, SP