Four-dimensional phase-contrast vastly undersampled isotropic projection reconstruction (4D PC-VIPR) MR evaluation of the renal arteries in transplant recipients: Preliminary results
Four-dimensional phase-contrast vastly undersampled isotropic projection reconstruction (4D PC-VIPR) MR evaluation of the renal arteries in transplant recipients: Preliminary results
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DOI：
10.1002/jmri.25607
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发表时间：
2017-08-01
影响因子：
4.4
通讯作者：
Ozono, Seiichiro
中科院分区：
文献类型：
--
作者：
Motoyama, Daisuke;Ishii, Yasuo;Ozono, Seiichiro
目的评价四维相位衬度欠采样各向同性投影重建的性能结果：4D PC-VIPR在3.0T时显示肾内动脉与CTA比较，与动脉血流测定比较，与DUS比较。受试者为2011年7月至2015年6月期间在我院接受肾移植相关手术的25例患者。在形态学研究中，比较了7例活体移植受者的MRA/4D PC-VIPR（无钆对比剂）肾动脉分支显示情况与7例活体移植供体的CTA肾动脉分支显示情况。在流量测定研究中，肾动脉中的流速应用非增强MRA/4D PC-VIPR对12例受者的主动脉、节段动脉和叶间动脉进行了测量，并与DUS结果进行了比较。由6名观察员评定的二级至三级肾动脉分支描绘的平均置信水平为82.9-100%第4 ~ 5支为60.8-89.7%（平均kappa值为0.588 [95%可信区间：0.522-0.653]）。4D PC-VIPR与DUS在收缩期和舒张期测量的总血流速度具有良好的相关性（收缩期r=0.902，P < 0.001;舒张期r=0.734，P < 0.001）。结论4D PC-VIPR可在不使用造影剂的情况下提供移植肾内动脉的形态学和血流动力学信息。证据等级：2技术有效性：第2阶段J. MAGN. RESON。影像2017;46：595-603
PurposeTo assess the performance of four-dimensional phase-contrast vastly undersampled isotropic projection reconstruction (4D PC-VIPR) at 3.0T in depicting intrarenal arteries compared with computed tomography angiography (CTA), and its correlation with arterial flowmetry in comparison with Doppler ultrasonography (DUS).Materials and MethodsIn our prospective single-arm study, subjects were 25 patients who underwent renal transplant-related surgery at our hospital between July 2011 and June 2015. In the morphological study, depictions of renal artery branches delineated by magnetic resonance angiography (MRA)/4D PC-VIPR without gadolinium contrast agent were compared in seven living transplant recipients with the same kidney delineated by CTA in seven living transplant donors. In the flowmetric study, flow velocities in the renal (main stem), segmental, and interlobar arteries during systole and diastole were measured in 12 recipients using noncontrast MRA/4D PC-VIPR, and were compared with those obtained from DUS.ResultsConcerning MRA, average confidence levels of delineation rated by six observers for secondary to third level renal artery branches were 82.9-100% and for the fourth to fifth branches were 60.8-89.7% (average kappa value of 0.588 [95% confidence interval: 0.522-0.653]). Total flow velocities measured using 4D PC-VIPR and DUS demonstrated significant correlations during both systole and diastole with acceptable bias (r=0.902; P < 0.001 in systole and r=0.734; P < 0.001 in diastole).Conclusion4D PC-VIPR was useful in generating both morphological and hemodynamic information for evaluation of transplant intrarenal arteries without the need for contrast media. Level of Evidence: 2 Technical Efficacy: Stage 2 J. MAGN. RESON. IMAGING 2017;46:595-603