Using the baculovirus/insect cell system to study apoptosis.
Using the baculovirus/insect cell system to study apoptosis.
复制标题
使用杆状病毒/昆虫细胞系统研究细胞凋亡。
DOI：
10.1007/978-1-59745-457-5_24
复制
发表时间：
2007
期刊：
影响因子：
--
通讯作者：
Chejanovsky,Nor
中科院分区：
文献类型：
--
作者：
Chejanovsky,Nor
Apoptosis is a physiological program of cell suicide conserved in invertebrates and vertebrates. Apoptosis is crucial to the normal development of organisms and in tissue homeostasis, by promoting elimination of unwanted cells including damaged- or virusinfected cells. Because of the importance of programmed cell death for the survival of the organism a tight regulation is exerted at various activation levels of the cell-death machinery. The utilization of the baculovirusAutographa californicamultiple nucleopolyhedrovirus to identify genes that inhibit the apoptotic process will be described using a transfection-based approach, illustrated by identification of thep49gene.
