PROTOTYPE IMPLEMENTATION OF THE INTEGRATED GENOMIC DATABASE
PROTOTYPE IMPLEMENTATION OF THE INTEGRATED GENOMIC DATABASE
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DOI：
10.1006/cbmr.1994.1011
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发表时间：
1994-04-01
期刊：
影响因子：
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通讯作者：
SUHAI, S
中科院分区：
文献类型：
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作者：
RITTER, O;KOCAB, P;SUHAI, S
我们的目标是开发一个开放的软件系统来处理人类基因组数据。该系统被称为集成基因组数据库（IGD），将把来自许多基因组数据库和实验资源的信息整合到一个全面的目标端数据库（IGD TED）中。用户将访问前端客户端系统（IGD FRED），将感兴趣的数据下载到他们的计算机上，并将其与自己的本地数据合并。FRED将提供检索数据的持久存储和即时访问;友好的图形界面;查询、浏览、分析和编辑本地数据的工具;外部分析的界面;以及与外部世界通信的工具。TED将作为多个客户的只读资源通过网络（在线和离线）访问。它从主要数据库收集核苷酸和蛋白质序列和结构，基因组图谱，实验试剂，表型和书目数据，以及基因组中心和实验室产生的原始数据集。除了通过Gopher，WAIS，FTP和几种查询语言接口的TED基于字符的访问，我们将开发一个专门的前端客户端，IGD FRED，与自己的数据库管理器，基于ACEDB程序。FRED将支持序列特征图、染色体遗传和物理图以及克隆网格等实验对象的图形显示方法。FRED还将提供重要分析软件包和工具的接口，以便以其自己的格式向外部数据库提交数据。(C)1994年出版社出版。
We aim to develop an open software system to handle human genome data. The system, called Integrated Genomic Database (IGD), will integrate information from many genomic databases and experimental resources into a comprehensive target-end database (IGD TED). Users will access front-end client systems (IGD FRED) to download data of interest to their computers and merge them with their own local data. FREDs will provide persistent storage of, and instant access to, retrieved data; a friendly graphical interface; tools for querying, browsing, analyzing, and editing local data; interface to external analysis; and tools for communicating with the outside world. The TED will be accessible over the network (online and offline) as a read-only resource for multiple clients. It collects data from major databases for nucleotide and protein sequences and structures, genome maps, experimental reagents, phenotypes, and bibliographic data, and sets of raw data produced at genome centers and laboratories. Beside character-based access via Gopher, WAIS, FTP, and several query language interfaces to the TED, we will develop a specialized front-end client, IGD FRED, with its own database manager, based on the ACEDB program. The FRED will support graphical display methods for sequence feature maps, chromosomal genetic and physical maps, and experimental objects like clone grids, etc. FRED will also provide an interface to important analysis software packages and tools for submitting data to external databases in their own format. (C) 1994 Academic Press, Inc.