Prognostic significance of tumor doubling time in evaluating operability in pulmonary metastatic disease.
Prognostic significance of tumor doubling time in evaluating operability in pulmonary metastatic disease.
复制标题
肿瘤倍增时间在评估肺转移性疾病可操作性中的预后意义。
DOI：
10.1016/s0022-5223(19)42271-x
复制
发表时间：
1971
期刊：
影响因子：
--
通讯作者：
P. C. Adkins
中科院分区：
文献类型：
--
作者：
W. Joseph;D. Morton;P. C. Adkins
对肿瘤疾病生长和进展方法的更深入了解导致了用于控制原发性恶性肿瘤及其局部扩展的更广泛的手术的发展，并且长期幸存者的数量不断增加。由于这种方法，近年来越来越多地报道成功手术摘除这些幸存者中的孤立性肺转移病灶。 13 尽管提出了任意标准来评估转移性肺疾病的可操作性，但这些标准在机构和外科医生之间存在差异。此外，根据这些标准，切除后的结果往往令人失望。因此，需要一种更加统一和精确的方法来进行病例比较、可操作性评估和生存预测。肿瘤倍增时间的测量已被证明是一种准确且可重复的方法
A greater understanding of the methods of growth and progression of neoplastic disease has led to the development of more extensive operations for the control of primary malignancies and their local extensions, with an increasing number of longterm survivors. As a result of this approach, successful surgical extirpation of isolated pulmonary metastatic lesions in these survivors has been reported with increasing frequency in recent years. 13 Although arbitrary criteria have been suggested for evaluating the operability of metastatic pulmonary disease, these have varied among institutions and surgeons. Furthermore, the results after resection, based on these criteria, are often disappointing. Consequently, a more uniform and precise method is needed for comparison of cases, evaluation of operability, and prediction of survival. The measurement of the tumor doubling time has been demonstrated to be an accurate and reproducible method