Interspersed repeats and other mementos of transposable elements in mammalian genomes

Interspersed repeats and other mementos of transposable elements in mammalian genomes
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DOI:
10.1016/s0959-437x(99)00031-3
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发表时间:
1999-12-01
影响因子:
4
通讯作者:
Smit, AFA
Smit, AFA
中科院分区:
生物学2区
文献类型:
--
作者:
Smit, AFA

文献摘要

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人类基因组的大部分最终来源于转座元件。过去一年的观察结果使人们对这些元件及其在我们基因组中的残余部分的功能和影响产生了一些新的、令人惊讶的想法。许多由单个转座子插入产生的人类基因的新例子凸显了自私DNA对基因组进化的巨大贡献。
The bulk of the human genome is ultimately derived from transposable elements. Observations in the past year lead to some new and surprising ideas on functions and consequences of these elements and their remnants in our genome. The many new examples of human genes derived from single transposon insertions highlight the large contribution of selfish DNA to genomic evolution.