Behavioral and psychiatric correlates of brain responses to social feedback.
Behavioral and psychiatric correlates of brain responses to social feedback.
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大脑对社会反馈的反应的行为和精神相关性。
DOI：
10.1111/psyp.14413
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发表时间：
2024
期刊：
影响因子：
3.7
通讯作者：
Barch,DeannaM
中科院分区：
文献类型：
--
作者：
Rappaport,BrentI;Kujawa,Autumn;Arfer,KodiB;Pegg,Samantha;Kelly,Danielle;Jackson,JoshuaJ;Luby,JoanL;Barch,DeannaM
对同伴接受和拒绝的适应不良反应出现在青春期的许多精神疾病中;然而，各种疾病的同质性和异质性表明了社会功能受损的共同和独特机制。我们测试了这样一个假设，即社会反馈的处理方式与其他形式的反馈类似（例如，货币）通过检查大脑对社会接受和拒绝的反应与单独奖励和损失任务的行为表现之间的对应关系。我们还研究了这些大脑反应与抑郁和社交焦虑严重程度之间的关系。样本由113名16 - 21岁的青少年组成，他们在事件相关电位（ERP）任务中接受了虚拟同伴接受/拒绝反馈。我们使用时空主成分分析，并确定了一个组件一致的奖励积极性（RewP）或反馈消极性（FN）。社会接纳的RewP与奖励偏差或与损失回避相关的社会拒绝的FN没有显著相关。RewP和抑郁症严重程度之间的关系，虽然不显着，是一个类似的规模，以前的研究。探索性分析得出了一个显着的关系，较低的社会经济地位（SES）和钝化RewP和较低的SES和提高损失避免和钝化奖励偏差。这些发现建立在先前工作的基础上，以提高我们对大脑对社会反馈的反应功能的理解，同时也为进一步研究提供了一条途径，即贫困通过社会和奖励学习机制导致抑郁症。
Maladaptive responses to peer acceptance and rejection arise in numerous psychiatric disorders in adolescence; yet, homogeneity and heterogeneity across disorders suggest common and unique mechanisms of impaired social function. We tested the hypothesis that social feedback is processed similarly to other forms of feedback (e.g., monetary) by examining the correspondence between the brain's response to social acceptance and rejection and behavioral performance on a separate reward and loss task. We also examined the relationship between these brain responses and depression and social anxiety severity. The sample consisted of one hundred and thirteen 16–21‐year olds who received virtual peer acceptance/rejection feedback in an event‐related potential (ERP) task. We used temporospatial principal component analysis and identified a component consistent with the reward positivity (RewP) or feedback negativity (FN). RewP to social acceptance was not significantly related to reward bias or the FN to social rejection related to loss avoidance. The relationship between RewP and depression severity, while nonsignificant, was of a similar magnitude to prior studies. Exploratory analyses yielded a significant relationship between lower socioeconomic status (SES) and blunted RewP and between lower SES and heightened loss avoidance and blunted reward bias. These findings build on prior work to improve our understanding of the function of the brain's response to social feedback, while also suggesting a pathway for further study, whereby poverty leads to depression via social and reward learning mechanisms.