Spectral quality control in motion-corrupted single-voxel J-difference editing scans: An interleaved navigator approach
Spectral quality control in motion-corrupted single-voxel J-difference editing scans: An interleaved navigator approach
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DOI：
10.1002/mrm.21337
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发表时间：
2007-10-01
影响因子：
3.3
通讯作者：
Phillips, M. D.
中科院分区：
文献类型：
--
作者：
Bhattacharyya, P. K.;Lowe, M. J.;Phillips, M. D.
运动对频谱质量有不利影响，需要在MR波谱（MRS）扫描中正确识别。基于谱减法的技术（如J-差编辑）更容易受到受受试者运动的影响，其中运动可能导致假峰或低效的峰减法。在MEGA点分辨光谱（MEGA-PRESS）序列中引入基于水信号的交错导航扫描，并在逐个拍摄的基础上采集数据，跟踪扫描仪内的受试者运动，识别运动损坏的数据并从数据集中排除。在枕叶皮层进行T-氨基丁酸（GABA）编辑扫描，可以从数据集中检索适当编辑的GABA光谱，否则将因运动而被丢弃。这项研究证明了独立的运动评估在J-差分编辑中的重要性。
Motion has an adverse effect on spectral quality and needs to be properly identified in MR spectroscopy (MRS) scans. Spectral subtraction-based techniques like J-difference editing are prone to be affected more by subject motion where motion can result in false peaks or inefficient subtraction of peaks. Introducing a water signal-based interleaved navigator scan in the MEGA point-resolved spectroscopy (MEGA-PRESS) sequence and acquiring data on a shot-by-shot basis, subject motion inside a scanner was tracked and motion-corrupted data were identified and excluded from the dataset. Performing a T-aminobutyric acid (GABA) editing scan at the occipital cortex, it was possible to retrieve a properly edited GABA spectrum from a dataset otherwise to be discarded due to motion. This study demonstrates the importance of independent motion assessment in J-difference editing.