Neurofilament architecture of superior and mesial premotor cortex in the human brain
Neurofilament architecture of superior and mesial premotor cortex in the human brain
复制标题
DOI：
10.1097/00001756-199705060-00026
复制
发表时间：
1997-05-06
期刊：
影响因子：
1.7
通讯作者：
Froment, JC
中科院分区：
文献类型：
--
作者：
Baleydier, C;Achache, P;Froment, JC
用抗神经丝蛋白的单抗(SMI-32)对两个人脑的前运动皮质进行了免疫化学研究，并与尼氏染色、髓鞘染色、细胞色素氧化酶染色和乙酰胆碱酯酶染色等其他构筑技术进行了比较，以区分皮质的细分。SMI-32免疫反应技术提供了4区、尾侧6区(6C区)和吻侧6区(6R区)特有的“神经丝构筑”模式。特别是，6区的两个细分之间的区别，这是很难用通常的细胞化学或酶构筑技术来理解的，这一点在这种技术中显得非常明显。因此，可以将Vogts的6aα区和6aβ区定位于背外侧凸面，将补充运动区和补充前运动区定位于大脑半球内侧壁。
MONOCLONAL antibody (SMI-32) to neurofilament protein was used in an immunochemical study of the premotor cortex of two human brains in comparison with other architectonic techniques such as Nissl, myelin, cytochrome-oxidase and acetylcholinesterase staining in order to distinguish cortical subdivisions. SMI-32 immunoreactivity technique provides 'neurofilament architecture' patterns specific to area 4, caudal area 6 (area 6c) and rostral area 6 (area 6r). Particularly, the distinction between the two subdivisions of area 6, which is difficult to appreciate with the usual cytochemical or enzyme architectonic techniques, appears very apparent with this technique. Hence, it was possible to localize the topographic boundaries of area 6a alpha and 6a beta of the Vogts on the dorso-lateral convexity and the supplementary motor area and the presupplementary motor area on the mesial wall of the hemisphere.