A survey of rodent-borne pathogens carried by wild Rattus spp. in Northern Vietnam
A survey of rodent-borne pathogens carried by wild Rattus spp. in Northern Vietnam
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DOI：
10.1017/s0950268812002385
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发表时间：
2013-09-01
影响因子：
4.2
通讯作者：
Arikawa, J.
中科院分区：
文献类型：
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作者：
Koma, T.;Yoshimatsu, K.;Arikawa, J.
为了检查越南河内和海丰城市地区大鼠携带的人类病原体的流行情况，我们于2011年1月活捕了100只大鼠，并对它们进行了细菌和病毒的筛选。大鼠血清中检出问号钩端螺旋体抗体（22.0%）、首尔病毒抗体（14.0%）和鼠戊型肝炎病毒抗体（23.0%），未检出鼠疫耶尔森氏菌抗体。抗L.问号和首尔病毒仅在成年大鼠中发现。相反，在幼年和亚成年大鼠中也发现了大鼠戊型肝炎病毒的抗体，表明大鼠戊型肝炎病毒的传播方式与L.问号和首尔病毒。此外，在褐家鼠中发现的首尔病毒的S和M片段的系统发育分析表明，来自海丰和河内的首尔病毒形成不同的分支。人类暴露于这些病原体已成为一个重大的公共卫生问题。
To examine the prevalence of human pathogens carried by rats in urban areas in Hanoi and Hai Phong, Vietnam, we live-trapped 100 rats in January 2011 and screened them for a panel of bacteria and viruses. Antibodies against Leptospira interrogans (22.0%), Seoul virus (14.0%) and rat hepatitis E virus (23.0%) were detected in rats, but antibodies against Yersinia pestis were not detected. Antibodies against L. interrogans and Seoul virus were found only in adult rats. In contrast, antibodies to rat hepatitis E virus were also found in juvenile and sub-adult rats, indicating that the transmission mode of rat hepatitis E virus is different from that of L. interrogans and Seoul virus. Moreover, phylogenetic analyses of the S and M segments of Seoul viruses found in Rattus norvegicus showed that Seoul viruses from Hai Phong and Hanoi formed different clades. Human exposure to these pathogens has become a significant public health concern.