The life span of new neurons in a song control nucleus of the adult canary brain depends on time of year when these cells are born.
The life span of new neurons in a song control nucleus of the adult canary brain depends on time of year when these cells are born.
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成年金丝雀大脑的歌曲控制核中新神经元的寿命取决于这些细胞出生的时间。
DOI：
10.1073/pnas.91.17.7849
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发表时间：
1994
影响因子：
11.1
通讯作者：
Alvarez-Buylla,A
中科院分区：
文献类型：
--
作者：
Nottebohm,F;O'Loughlin,B;Gould,K;Yohay,K;Alvarez-Buylla,A
高发声中心（HVC）神经元标记的成年雄性金丝雀全身注射[3H]胸苷的数量取决于季节和生存时间。这是真实的HVC神经元投射到强大的archistriatum核和其他HVC神经元，不能逆行填充从强大的archistriatum核。10月份注射并在40天后杀死的鸟类，其标记的HVC神经元是5月份注射并在40天后杀死的鸟类的两倍。然而，当鸟类被允许存活4个月时，这种差异变得更大（5倍）。虽然超过一半的春季出生的神经元在40天到4个月之间消失，但在4个月的存活时间点，秋季出生的神经元数量没有减少。我们推断，季节性变量会影响成年期出生的HVC神经元的寿命。
The number of high vocal center (HVC) neurons labeled in adult male canaries by systemic injections of [3H]thymidine depended on season and survival time. This was true for HVC neurons projecting to the robust nucleus of the archistriatum and for other HVC neurons that could not be retrogradely filled from the robust nucleus of the archistriatum. Birds injected in October and killed 40 days later had twice as many labeled HVC neurons as birds injected in May and killed 40 days later. However, this difference became much larger (5 times) when the birds were allowed to survive for 4 months. Whereas more than half of the spring-born neurons disappeared between 40 days and 4 months, there was no reduction in the number of fall-born neurons present at the 4-month survival point. We infer that seasonal variables affect the life span of HVC neurons born in adulthood.