ON ULTRASTRUCTURE OF FOLLICLES AND ISOLATED FOLLICULAR GRANULOSA CELLS OF PORCINE OVARY
ON ULTRASTRUCTURE OF FOLLICLES AND ISOLATED FOLLICULAR GRANULOSA CELLS OF PORCINE OVARY
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DOI：
10.1007/bf01901700
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发表时间：
1967-01-01
期刊：
影响因子：
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通讯作者：
BJERSING, L
中科院分区：
文献类型：
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作者：
BJERSING, L
猪卵巢的初级、次级和小三级卵泡的颗粒细胞内质网稀疏，大部分呈颗粒状。大三级卵泡的颗粒细胞内质网表现出明显的增殖迹象。有些细胞甚至含有内质网膜的螺旋，本质上是无颗粒的种类。颗粒和无颗粒类型的内质网膜之间的直接连续性以及无颗粒膜的不断增加表明这些膜可能起源于颗粒膜。从大的三级卵泡中分离出的颗粒细胞 显微解剖和体外保存显示与完整大三级卵泡的颗粒细胞基本相同的超微结构。一些脂滴似乎位于内质网的空腔中。表明这些液滴含有类固醇激素合成的前体物质。最后，无颗粒内质网的发育，包括大第三卵泡的一些颗粒细胞中螺纹的出现，表明类固醇合成可能发生在这些卵泡颗粒细胞中。
The endoplasmic reticulum in granulosa cells of primary, secondary, and small tertiary follicles of the porcine ovary is sparse and largely of the granular type.In granulosa cells of large tertiary follicles the endoplasmic reticulum shows distinct signs of proliferation. Some cells even contain whorls of endoplasmic reticulum membranes, essentially of the agranular variety.Direct continuity between endoplasmic reticulum membranes of the granular and agranular type as well as the continuous increase in agranular membranes suggest that these membranes may originate from the granular membranes.Granulosa cells isolated from large tertiary follicles by microdissection and keptin vitroshow essentially the same ultrastructure as granulosa cells of intact large tertiary follicles.Some lipid droplets appear to be localized in cavities of the endoplasmic reticulum. It is suggested that the droplets contain precursor material for steroid hormone synthesis.Finally, the development of the agranular endoplasmic reticulum including the appearance of whorls in some granulosa cells of large tertiary follicles indicates that steroid synthesis may occur in such follicular granulosa cells.