White Matter Injury and Recovery after Hypertensive Intracerebral Hemorrhage.
White Matter Injury and Recovery after Hypertensive Intracerebral Hemorrhage.
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DOI：
10.1155/2017/6138424
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发表时间：
2017
影响因子：
--
通讯作者：
Feng H
中科院分区：
文献类型：
--
作者：
Zuo S;Pan P;Li Q;Chen Y;Feng H
高血压性脑出血（ICH）极有可能引起患者脑白质损伤。通过对高血压脑出血后脑白质损伤的持续研究，我们对其发生发展的病理生理机制有了更深刻的认识。同时，我们发现了一系列针对白质修复的药物和治疗方法。在目前的现实中，高血压脑出血后脑白质损伤的研究范式相对陈旧或不完整，研究中仍存在许多不足。面对脑卒中研究视角的深刻变化，我们认为将透镜状纹状动脉、下丘脑-丘脑-基底节区神经核以及位于内囊内的白质纤维结合起来，将有利于白质损伤与修复的研究。本文对高血压脑出血后脑白质损伤与修复的研究进行了分类和分析，并对目前研究的不足进行了反思。我们希望能帮助研究者进一步探索和研究高血压脑出血后的脑白质损伤和修复。
Hypertensive intracerebral hemorrhage (ICH) could very probably trigger white matter injury in patients. Through the continuous study of white matter injury after hypertensive ICH, we achieve a more profound understanding of the pathophysiological mechanism of its occurrence and development. At the same time, we found a series of drugs and treatment methods for the white matter repair. In the current reality, the research paradigm of white matter injury after hypertensive ICH is relatively obsolete or incomplete, and there are still lots of deficiencies in the research. In the face of the profound changes of stroke research perspective, we believe that the combination of the lenticulostriate artery, nerve nuclei of the hypothalamus-thalamus-basal ganglia, and the white matter fibers located within the capsula interna will be beneficial to the research of white matter injury and repair. This paper has classified and analyzed the study of white matter injury and repair after hypertensive ICH and also rethought the shortcomings of the current research. We hope that it could help researchers further explore and study white matter injury and repair after hypertensive ICH.