THE RELATIONSHIP BETWEEN OXYGEN DELIVERY AND CONSUMPTION DURING FLUID RESUSCITATION OF HYPOVOLEMIC AND SEPTIC SHOCK
THE RELATIONSHIP BETWEEN OXYGEN DELIVERY AND CONSUMPTION DURING FLUID RESUSCITATION OF HYPOVOLEMIC AND SEPTIC SHOCK
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DOI：
10.1378/chest.85.3.336
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发表时间：
1984-01-01
期刊：
影响因子：
9.6
通讯作者：
FALK, JL
中科院分区：
文献类型：
--
作者：
KAUFMAN, BS;RACKOW, EC;FALK, JL
研究了在液体复苏过程中增加O2输送（≥ DO 2）对8名感染性休克患者和5名低血容量性休克患者的O2消耗（≥ VO 2）的影响。在败血性休克组中，DO 2从315 ± 0.05增加到315 ± 0.05。29到424 .+-. 25 ml/min/m2（P < 0.01），并且VO 2从134 ± 0.05增加到134 ± 0.05。8到151 .+-. 7ml/min/m2（P < 0.01）。在低血容量性休克组中，DO 2从239 ± 0.01增加到239 ± 0.01。26到386 .+-. 48 ml/min/m2（P < 0.01），并且VO 2从96 ± 0.01增加到98 ± 0.01。9到135 .+-. 6 ml/min/m2（P < 0.01）。在感染性休克和低血容量性休克患者之间，DO 2或VO 2的增加没有显著差异。显然，在低血容量性休克和脓毒性休克期间，通过液体复苏增加DO 2或VO 2或VO 2。
The effects of increasing O2 delivery (.ovrhdot.DO2) on O2 consumption (.ovrhdot.VO2) in 8 patients with septic shock and 5 patients with hypovolemic shock were studied during fluid resuscitation. In the septic shock group, .ovrhdot.DO2 increased from 315 .+-. 29 to 424 .+-. 25 ml/min per m2 (P < 0.01) and .ovrhdot.VO2 increased from 134 .+-. 8 to 151 .+-. 7 ml/min per m2 (P < 0.01). In the hypovolemic shock group, .ovrhdot.DO2 increased from 239 .+-. 26 to 386 .+-. 48 ml/min per m2 (P < 0.01) and .ovrhdot.VO2 increased from 96 .+-. 9 to 135 .+-. 6 ml/min per m2 (P < 0.01). There was no significant diffference in either the increase in .ovrhdot.DO2 or .ovrhdot.VO2 between the septic shock and hypovolemic shock patients. Evidently, increasing .ovrhdot.DO2 by fluid resuscitation increases .ovrhdot.VO2 during both hypovolemic and septic shock.