Incidence and prevalence of recognised and unrecognised myocardial infarction in women - The Reykjavik Study
Incidence and prevalence of recognised and unrecognised myocardial infarction in women - The Reykjavik Study
复制标题
DOI：
10.1053/euhj.1998.0980
复制
发表时间：
1998-07-01
影响因子：
39.3
通讯作者：
Thorgeirsson, G
中科院分区：
文献类型：
--
作者：
Jonsdottir, LS;Sigfusson, N;Thorgeirsson, G
目的-确认和未确认的心肌梗死的发病率和患病率确定在冰岛队列研究的13 000名妇女（雷克雅未克研究），随后长达29年（平均15年）。方法和结果妇女参加雷克雅未克研究，出生于1908年和1935年之间，在1968年至1991年的五个阶段进行了检查。健康调查包括冠心病病史和心电图表现。截至1992年底，从医院、尸检记录和死亡证明中检索的数据确定了596例致命和非致命心肌梗塞（61例在检查前，320例非致命和215例致命）。确诊心肌梗死的发生率范围为35-39岁时22例/100 000/年至75-79岁时1800例/100 000/年。未识别心肌梗死的发生率范围为35岁时的1800例/100 000/年至75岁时的219例/100 000/年。33%的非致命性心肌梗死未被识别。较年轻的年龄组（40%）比较年长的年龄组（27%）更多。年龄和日历年影响已确认的心肌梗死的患病率。1990年，35岁时为1.3/1000，75岁时为60/1000。流行率呈时间趋势，从1968年至1992年，所有年龄组的流行率增加了两倍。对于未被确认的心肌梗死，患病率上升，从0.9/1000在35岁至19.2/1000在75 years，虽然没有明显的时间trends.Conclusion心肌梗死在女性是非常年龄依赖性的，发病率和患病率不断增加，并随着年龄的急剧增长。从1968年到1992年，公认的心肌梗死的患病率有显著的增加趋势。未识别的非致命性梗死的比例范围从最大年龄组的27%到最小年龄组的40%。平均而言，这种形式的冠心病与男性一样常见。
Aims The incidence and prevalence of recognised and unrecognised myocardial infarction were determined in the Icelandic cohort study of 13 000 women (the Reykjavik Study), followed for up to 29 years (mean 15 years).Methods and Results Women attending the Reykjavik Study, born between 1908 and 1935, were examined in five stages from 1968 to 1991. A health survey included history and ECG manifestations of coronary heart disease. Data retrieved from hospitals, autopsy records and death certificates identified 596 fatal and non-fatal myocardial infarctions to the end of 1992 (61 prior to examination, 320 non-fatal and 215 fatal). The incidence of recognised myocardial infarction ranged from 22 cases/100 000/year at 35-39 years to 1800 cases/100 000/year at 75-79 years. The incidence of unrecognised myocardial infarction ranged from 1800 cases/100 000/year at 35 years to 219 cases/100 000/year at 75 years. Thirty-three percent of non-fatal myocardial infarctions were unrecognised. More occurred in the younger age groups (40%) than in the older (27%). The prevalence of recognised myocardial infarction was influenced by age and calendar year. In 1990, it was 1.3/1000 at 35 years and 60/1000 at 75 years. Prevalence showed a time trend, tripling in all age groups from 1968-1992. For unrecognised myocardial infarction, prevalence rose from 0.9/1000 at 35 years to 19.2/1000 at 75 years, although there was no evident time trend.Conclusion Myocardial infarction in women is very age-dependent, with both incidence and prevalence increasing continuously and steeply with age. There was a significant trend for an increase in prevalence of recognised myocardial infarction from 1968 to 1992. The proportion of unrecognised non-fatal infarctions ranged from 27% in the oldest age group to 40% in the youngest. On average, this form of coronary heart disease is as common as in men.