Spatial summation in the human fovea: the effect of optical aberrations and fixational eye movements

Spatial summation in the human fovea: the effect of optical aberrations and fixational eye movements
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人类中央凹的空间总和:光学像差和注视眼球运动的影响

DOI:
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发表时间:
2018
期刊:
bioRxiv
影响因子:
--
通讯作者:
J. Morgan
J. Morgan
中科院分区:
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文献类型:
--
作者:
William S. Tuten;R. F. Cooper;Pavan Tiruveedhula;A. Dubra;A. Roorda;N. Cottaris;D. Brainard;J. Morgan

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支持空间视觉的神经机制的心理物理学推断可能会被光学像差和注视眼球运动引入的不确定性所破坏,特别是在视觉系统的神经元颗粒很好的中央凹中。我们研究了这些前神经因素对人类中央凹中明视空间总和的影响,使用自适应光学扫描光检眼镜,该检眼镜提供对光学像差和视网膜刺激运动的控制。与以前的结果一致,Ricco的面积完全总和包括多个光感受器时,测量与普通量的眼像差和视网膜刺激运动。当这两个因素最小化实验,总和面积基本上没有变化,这表明中央凹空间总和是有限的后受体神经池。我们将我们的行为数据与由视觉系统的生理学启发的前端模型生成的预测进行了比较,并且能够使用固定空间范围的单个后感受器求和滤波器捕获在有和没有视网膜前因素的情况下获得的求和曲线的形状。根据我们的数据和模型,大细胞视觉通路中的神经元,如阳伞神经节细胞,提供了中央凹Ricco区的候选神经相关物。
Psychophysical inferences about the neural mechanisms supporting spatial vision can be undermined by uncertainties introduced by optical aberrations and fixational eye movements, particularly in fovea where the neuronal grain of the visual system is fine. We examined the effect of these pre-neural factors on photopic spatial summation in the human fovea using a custom adaptive optics scanning light ophthalmoscope that provided control over optical aberrations and retinal stimulus motion. Consistent with previous results, Ricco’s area of complete summation encompassed multiple photoreceptors when measured with ordinary amounts of ocular aberrations and retinal stimulus motion. When both factors were minimized experimentally, summation areas were essentially unchanged, suggesting that foveal spatial summation is limited by post-receptoral neural pooling. We compared our behavioral data to predictions generated with a physiologically-inspired front-end model of the visual system, and were able to capture the shape of the summation curves obtained with and without pre-retinal factors using a single post-receptoral summing filter of fixed spatial extent. Given our data and modeling, neurons in the magnocellular visual pathway, such as parasol ganglion cells, provide a candidate neural correlate of Ricco’s area in the central fovea.
视网膜图像运动在空间视觉范围内的好处。
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