Complete genome sequence of bacteriocin-producing Lactobacillus plantarum KLDS1.0391, a probiotic strain with gastrointestinal tract resistance and adhesion to the intestinal epithelial cells
Complete genome sequence of bacteriocin-producing Lactobacillus plantarum KLDS1.0391, a probiotic strain with gastrointestinal tract resistance and adhesion to the intestinal epithelial cells
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产生细菌素的植物乳杆菌KLDS1.0391的完整基因组序列，一种具有胃肠道抵抗力并粘附于肠上皮细胞的益生菌菌株
DOI：
10.1016/j.ygeno.2017.06.008
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发表时间：
2017-10-01
期刊：
影响因子：
4.4
通讯作者：
Meng, Xiang-Chen
中科院分区：
文献类型：
--
作者：
Jia, Fang-Fang;Zhang, Lu-Ji;Meng, Xiang-Chen
植物乳杆菌 KLDS1.0391 是从传统发酵乳制品中分离出来的益生菌菌株，经鉴定可产生针对革兰氏阳性和革兰氏阴性细菌的细菌素。前期研究表明，该菌株对胃肠道应激具有较高的抵抗力，并且与肠上皮细胞（Caco-2）具有较高的粘附能力。我们报道了该菌株的整个基因组序列，其中包含一条环状 2,886,607 bp 染色体和三个环状质粒。鉴定了与细菌素生物合成、胃肠道环境应激抵抗和粘附性能相关的基因。植物乳杆菌KLDS1.0391的全基因组序列将有助于其在食品工业中的应用。 (C) 2017 Elsevier Inc. 保留所有权利。
Lactobacillus plantarum KLDS1.0391 is a probiotic strain isolated from the traditional fermented dairy products and identified to produce bacteriocin against Gram-positive and Gram-negative bacteria. Previous studies showed that the strain has a high resistance to gastrointestinal stress and has a high adhesion ability to the intestinal epithelial cells (Caco-2). We reported the entire genome sequence of this strain, which contains a circular 2,886,607-bp chromosome and three circular plasmids. Genes, which are related to the biosynthesis of bacteriocins, the stress resistance to gastrointestinal tract environment and adhesive performance, were identified. Whole genome sequence of Lactobacillus plantarum KLDS1.0391 will be helpful for its applications in food industry. (C) 2017 Elsevier Inc. All rights reserved.