Medication and Falls: Risk and Optimization
Medication and Falls: Risk and Optimization
复制标题
DOI：
10.1016/j.cger.2010.06.007
复制
发表时间：
2010-11-01
影响因子：
3.3
通讯作者：
Cumming, Robert G.
中科院分区：
文献类型：
--
作者：
Boyle, Nichola;Naganathan, Vasi;Cumming, Robert G.
在过去的30年里，药物与福尔斯之间的关系得到了广泛的研究，越来越多的证据表明两者之间存在因果关系。特定类别的药物和服用的药物总数都与福尔斯有关。本文综述了老年人发生药物相关不良事件（如福尔斯）的风险更高的一些原因，并讨论了药物在一般和多种药物中的作用。（同时使用多种药物）对跌倒风险的影响，重点关注社区居住的老年人我们批判性地评估了以下证据：苯二氮卓类药物和抗抑郁药等特定类别的药物会增加跌倒风险，并且可以通过针对药物的干预措施来预防福尔斯
The association between drugs and falls has been widely studied in the past 3 decades with increasingly robust evidence of a causal link Both specific classes of drugs and the total number of drugs taken are associated with falls This review examines some of the reasons why older people are at greater risk of drug-related adverse events such as falls We discuss the role of drugs in general and polypharmacy (the concurrent use of multiple drugs) on the risk of falling with a focus on community-dwelling older people We critically appraise the evidence that specific classes of drugs such as benzodiazepines and antidepressants increase the risk of falling and that falls can be prevented through interventions that target medications