GenCLiP 3: mining human genes' functions and regulatory networks from PubMed based on co-occurrences and natural language processing

GenCLiP 3: mining human genes' functions and regulatory networks from PubMed based on co-occurrences and natural language processing
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GenCLiP 3:基于共现和自然语言处理,从 PubMed 挖掘人类基因的功能和调控网络。

DOI:
10.1093/bioinformatics/btz807
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发表时间:
2020-03-15
期刊:
影响因子:
5.8
通讯作者:
Huang, Zhong-Xi
Huang, Zhong-Xi
中科院分区:
生物学3区
文献类型:
--
作者:
Wang, Jia-Hong;Zhao, Ling-Feng;Huang, Zhong-Xi

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摘要:我们提出了一个网络服务器 GenCLiP 3,它是 GenCLiP 2.0 的更新版本,用于增强对人类基因功能和调控网络的分析,具有以下改进:(i)从整个 PubMed 数据库中准确识别具有极性和方向性的分子相互作用; (ii) 支持布尔搜索,可定制多词搜索,快速检索功能相关基因; (iii) 通过新的评分方法加强基因和关键词之间的关联; (iv) PubMed FTP 文献发布后的每日更新。
A Summary: We present a web server, GenCLiP 3, which is an updated version of GenCLiP 2.0 to enhance analysis of human gene functions and regulatory networks, with the following improvements: (i) accurate recognition of molecular interactions with polarity and directionality from the entire PubMed database; (ii) support for Boolean search to customize multiple-term search and to quickly retrieve function-related genes; (iii) strengthened association between gene and keyword by a new scoringmethod; and (iv) daily updates following literature release at PubMed FTP.