Decoration of Nanofibrous Paper Chemiresistors with Dendronized Nanoparticles toward Structurally Tunable Negative-Going Response Characteristics to Human Breathing and Sweating
Decoration of Nanofibrous Paper Chemiresistors with Dendronized Nanoparticles toward Structurally Tunable Negative-Going Response Characteristics to Human Breathing and Sweating
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DOI：
10.1002/admi.201700380
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发表时间：
2017-11-23
影响因子：
5.4
通讯作者：
Zhong, Chuan-Jian
中科院分区：
文献类型：
--
作者：
Yan, Shan;Liu, Xin;Zhong, Chuan-Jian
用于人体性能监测的可穿戴呼吸或汗液传感器阵列的开发对于在各种环境条件下提供个性化健康信息越来越重要。一个主要的挑战是缺乏对水分主导的呼吸和出汗过程唯一响应的传感元件，这对于区分其他化学或生物物种与水分主导的环境至关重要。本文报道了一类新型的装饰有树枝状纳米颗粒的纳米纤维纸化学电阻器，其对人类呼吸和出汗表现出结构可调和负向响应。该纳米复合材料装置的特点是来自多层纳米纤维纸的柔性膜型支架作为生物相容性基质和具有可调尺寸和形状的树枝状金纳米颗粒，以实现结构多样性和分子敏感性。新奇的关键要素包括固定化的聚（醚-酯）树枝状分子与寡聚乙二醇间隔金纳米粒子和部分互穿树枝状分子之间的氢键和货车德瓦尔斯相互作用的组合，导致可调的和独特的响应特性的呼吸和出汗过程。结果表明，第一个例子的纳米纤维纸化学电阻器装饰树枝状纳米粒子作为一个有前途的新策略，构建可穿戴呼吸和汗液传感器的传感接口。
The development of wearable breath or sweat sensor arrays for human performance monitoring is increasingly important for providing personalized health information under various environmental conditions. A major challenge is the lack of sensing elements responsive uniquely to moisture-dominated breathing and sweating processes, which is critical for differentiating other chemical or biological species from the moisture-dominated environment. Here a novel class of nanofibrous paper chemiresistors decorated with dendronized nanoparticles that exhibit structurally tunable and negative-going responses to human breathing and sweating is reported. The nanocomposite device features flexible membrane-type scaffold derived from multilayered nanofibrous paper as a biocompatible matrix and dendronized gold nanoparticles with tunable sizes and shapes to enable structural diversity and molecular sensitivity. Key elements of novelty include the immobilization of poly(ether-ester) dendrons with oligoethylene glycol spacers on gold nanoparticles and the combination of hydrogen bonding and van der Waals interactions between partially interpenetrating dendrons, leading to tunable and unique response characteristics to breathing and sweating processes. The results demonstrate the first example of nanofibrous paper chemiresistors decorated with dendronized nanoparticles as a promising new strategy toward constructing sensing interfaces for wearable breath and sweat sensors.