RESET OF HIPPOCAMPAL RHYTHMICAL ACTIVITIES BY AFFERENT STIMULATION
RESET OF HIPPOCAMPAL RHYTHMICAL ACTIVITIES BY AFFERENT STIMULATION
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DOI：
10.1016/0361-9230(78)90057-6
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发表时间：
1978-01-01
影响因子：
3.8
通讯作者：
GARCIAAUSTT, E
中科院分区：
文献类型：
--
作者：
BUNO, W;GARCIASANCHEZ, JL;GARCIAAUSTT, E
毒扁豆碱诱导的从固定的局部麻醉大鼠的背侧海马记录节律和单位活动。θ之间的相关性和节律单位的活动及其变化的海马传入刺激。传入神经的电刺激重置θ和有节奏的单位活动。刺激后θ显示了一个可变的频率，这取决于刺激的结构。较低的频率诱发隔，较高的频率由内嗅和网状结构刺激。当θ。由于自发性消失或由于穹窿上级或隔膜的损伤而导致心律不齐，未观察到重置。θ的复位节律和单位活动的传入刺激表明，海马可能参与定时机制。
Physostigmine induced .theta. rhythm and unit activity were recorded from the dorsal hippocampus in immobilized locally anesthetized rats. Correlations between .theta. and rhythmical unit activity and their modifications by hippocampal afferent stimulation were studied. Electrical stimulation of afferents reset .theta. and rhythmical unit activity in phase. Poststimulus .theta. displayed a variable frequency which depended on the structure stimulated. Lower frequencies were evoked by septal, higher frequencies by entorhinal and reticular formation stimulations. When .theta. rhythms were absent either by spontaneous disappearance or as a consequence of lesions in the fornix superior or septum, the reset was not observed. The reset of the .theta. rhythms and unit activity by afferent stimulation suggested that the hippocampus may participate in timing mechanisms.