A highly efficient and selective synthesis of 1,2,3-triazole linked saccharide nucleosides via "click chemistry"

A highly efficient and selective synthesis of 1,2,3-triazole linked saccharide nucleosides via "click chemistry"
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通过“点击化学”高效选择性合成 1,2,3-三唑连接糖核苷

DOI:
10.1080/15257770801944055
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发表时间:
2008-01-01
影响因子:
1.3
通讯作者:
Wu, Jun
Wu, Jun
中科院分区:
生物学4区
文献类型:
--
作者:
Ding, Haixin;Yang, Ruchun;Wu, Jun

文献摘要

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通过3‘-叠氮-2’-脱氧胸腺嘧啶核苷和炔丙基碳水化合物的“点击化学”,高产率和高选择性地合成了一系列1,2,3-三氮唑连接的糖核苷。
A series of 1,2,3-triazole linked saccharide nucleosides were synthesized in high yield and selectivity via "click chemistry" of the 3'-azido-2'-deoxythymidine and the propargyl carbohydrates.[GRAPHICS]