Diabetes mellitus and its association with central obesity and disability among older adults: A global perspective
Diabetes mellitus and its association with central obesity and disability among older adults: A global perspective
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DOI：
10.1016/j.exger.2015.02.010
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发表时间：
2015-04-01
影响因子：
3.9
通讯作者：
Maria Haro, Josep
中科院分区：
文献类型：
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作者：
Tyrovolas, Stefanos;Koyanagi, Ai;Maria Haro, Josep
该研究的目的是评估各种因素与II型糖尿病（DM）之间的关联，特别强调中心性肥胖的指标，并比较DM对9个国家老年人（>= 50岁）残疾的影响。有52 946名年龄≥ 18岁的人的数据，他们参加了世卫组织2007年至2012年进行的全球老龄化和成人健康研究以及欧洲老龄化问题合作研究。DM定义为医生诊断的自我报告。测量身高、体重和腰围。使用WHODAS II问卷评估残疾状况。DM的总体患病率为7.9%，范围为3.8%（加纳）至17.6%（墨西哥）。腰围增加10 cm和腰高比>0.5分别与糖尿病风险显著增加1.26（印度）至1.77（芬兰）和1.68（中国，西班牙）至5.40（芬兰）倍相关。在墨西哥和南非没有观察到显著的关联。在调整人口统计学和吸烟的模型中，除墨西哥外，所有国家的糖尿病与显著较高的残疾状态相关。在模型中纳入与糖尿病相关的慢性病，根据国家不同程度地削弱了系数。相当大比例的老年人患有糖尿病。中心性肥胖可能是全球老年人群预防DM的关键因素。预防糖尿病，特别是在全球老年人群中预防糖尿病，可能有助于减轻残疾负担。(C)2015爱思唯尔公司All rights reserved.
The aim of the study was to evaluate the association between various factors and diabetes type II (DM) with a particular emphasis on indicators of central obesity, and to compare the effect of DM on disability among elder populations (>= 50 years old) in nine countries. Data were available for 52,946 people aged >= 18 years who participated in the WHO Study on global AGEing and adult health and the Collaborative Research on Ageing in Europe studies conducted between 2007 and 2012. DM was defined as self-report of physician diagnosis. Height, weight, and waist circumference were measured. Disability status was assessed with the WHODAS II questionnaire. The overall prevalence of DM was 7.9% and ranged from 3.8% (Ghana) to 17.6% (Mexico). A 10 cm increase in waist circumference and waist-to-height ratio of >0.5 were associated with a significant 1.26 (India) to 1.77 (Finland), and 1.68 (China, Spain) to 5.40 (Finland) times higher odds for DM respectively. No significant associations were observed in Mexico and South Africa. DM was associated with significantly higher disability status in all countries except Mexico in the model adjusted for demographics and smoking. The inclusion of chronic conditions associated with diabetes in the model attenuated the coefficients in varying degrees depending on the country. A considerable proportion of the studied older population had DM. Central obesity may be a key factor for the prevention of DM among older populations globally. Prevention of DM especially among the older population globally may contribute to reducing the burden of disability. (C) 2015 Elsevier Inc. All rights reserved.