Iron and Cobalt oxide and metallic nanoparticles prepared from ferritin
Iron and Cobalt oxide and metallic nanoparticles prepared from ferritin
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DOI：
10.1021/la0491100
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发表时间：
2004-11-09
期刊：
影响因子：
3.9
通讯作者：
Douglas, T
中科院分区：
文献类型：
--
作者：
Hosein, HA;Strongin, DR;Douglas, T
金属Fe和Co以及Fe和Co基氧化物纳米颗粒通过利用生物相关蛋白质铁蛋白的新方法制备。特别是，在水相中，铁和氢氧化钴纳米颗粒分别组装在马脾脏和无害李斯特菌衍生的铁蛋白中。将含有Fe或Co氧化物的铁蛋白转移到SiO2载体上并干燥，其中在暴露于高氧化环境期间除去蛋白质壳。还表明，金属氧化物颗粒可以通过在氢气中加热还原成相应的金属。X射线光电子能谱被用来表征的颗粒的组成和原子力显微镜被用来表征的纳米粒子的大小。根据Fe或Co负载量和/或所用铁蛋白的类型，可以在20-60埃的范围内产生金属和氧化物纳米颗粒。
Metallic Fe and Co and Fe- and Co-based oxide nanoparticles were prepared by a novel method utilizing the biologically relevant protein ferritin. In particular, iron and cobalt oxyhydroxide nanoparticles were assembled within horse spleen and Listeria innocua derived ferritin, respectively, in the aqueous phase. Ferritin containing either Fe or Co oxide was transferred and dried on a SiO2 support where the protein shell was removed during exposure to a highly oxidizing environment. It was also shown that the metal oxide particles could be reduced to the respective metal by heating in hydrogen. X-ray photoelectron spectroscopy was used to characterize the composition of the particles and atomic force microscopy was used to characterize the size of the nanoparticles. Depending on the Fe or Co loading and/or type of ferritin used, metallic and oxide nanoparticles could be produced within a range of 20-60 Angstrom.