Physiological and biochemical changes associated with acute experimental dehydration in the desert adapted mouse, Peromyscus eremicus.
Physiological and biochemical changes associated with acute experimental dehydration in the desert adapted mouse, Peromyscus eremicus.
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DOI：
10.14814/phy2.13218
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发表时间：
2017-03
影响因子：
2.5
通讯作者：
MacManes MD
中科院分区：
文献类型：
--
作者：
Kordonowy L;Lombardo KD;Green HL;Dawson MD;Bolton EA;LaCourse S;MacManes MD
描述适应特定环境的关键特征是理解表型如何进化的重要第一步。动物如何适应沙漠中常见的极端高温和干旱是这些过程中一个非常有趣的例子，几十年来一直是研究的焦点。与那些在非沙漠条件下对野生动物或圈养动物进行实验的研究相反，这里描述的研究利用了一个独特的环境室，为圈养的Peromyscus eremicus（仙人掌鼠）复制了沙漠条件。在这里，我们建立了每日饮水量和血清电解质的基线值，以及这些变量对急性实验性脱水的反应。总之，沼虾的日摄水量很低。它的血清电解质与许多先前研究过的动物不同，它对急性脱水的反应很强烈，尽管没有提示肾脏损害，这在哺乳动物中是不典型的。
Characterizing traits critical for adaptation to a given environment is an important first step in understanding how phenotypes evolve. How animals adapt to the extreme heat and aridity commonplace to deserts is an exceptionally interesting example of these processes, and has been the focus of study for decades. In contrast to those studies, where experiments are conducted on either wild animals or captive animals held in non‐desert conditions, the study described here leverages a unique environmental chamber that replicates desert conditions for captive Peromyscus eremicus (cactus mouse). Here, we establish baseline values for daily water intake and for serum electrolytes, as well as the response of these variables to acute experimental dehydration. In brief, P. eremicus daily water intake is very low. Its serum electrolytes are distinct from many previously studied animals, and its response to acute dehydration is profound, though not suggestive of renal impairment, which is atypical of mammals.